Vasopressin丨CAS 9034-50-8

Vasopressin is widely used in clinical medicine as both a therapeutic peptide and a physiological research tool. In healthcare, it is administered for the management of vasodilatory shock, particularly septic shock, where it helps restore vascular tone and support blood pressure when catecholamines are insufficient. It is also employed in the treatment of diabetes insipidus due to its antidiuretic activity, helping regulate water retention by acting on renal V2 receptors. Vasopressin plays a role in perioperative care to control bleeding through vasoconstriction and is sometimes used in gastrointestinal procedures to reduce portal pressure. In research settings, vasopressin serves as a biochemical standard for studying receptor signaling, cardiovascular regulation, renal water balance, and neuroendocrine pathways.

The primary benefits of vasopressin derive from its dual vasoconstrictive and antidiuretic properties, offering targeted physiological control in critical-care scenarios. It provides effective vasopressor activity that acts independently of adrenergic receptors, making it particularly valuable in patients with catecholamine-resistant shock. Its ability to promote water reabsorption reduces excessive urine output in diabetes insipidus and supports stabilization of fluid balance. Vasopressin also features predictable pharmacological behavior, rapid onset, and short duration of action, which allow precise titration in emergency and perioperative environments. In research applications, its well-characterized receptor interactions and signaling pathways make it a reliable model peptide for studying hormonal regulation and vascular physiology.