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Specifications
| Appearance | White crystals or crystalline powder |
| Purity | 99.0% min |
| Clarity of solution | Colorless, Clarity |
| Sulphate | 0.2% max |
| Chloride | 0.1% max |
| Relative substance | 0.5% max |
| Heavy metal | 0.002% max |
| Arsenic | 0.0002% max |
| Loss on drying | 0.2% max |
Applications
1. Buffering Agent
Acts as a zwitterionic buffer, particularly useful in biological and biochemical systems.
Provides pH stability in the acidic to near-neutral range, similar to other sulfonic acid-based biological buffers.
2. Intermediate in Organic Synthesis
Used as a chemical intermediate in the synthesis of:
Specialty surfactants
Pharmaceutical compounds
Ionic liquids and functionalized polymers
3. Biological and Biochemical Research
Studied for its biocompatibility and potential as a model compound for amino acid analogues.
Can be used in electrolyte formulation, enzyme studies, and chromatographic buffer systems.
4. Potential Use in Drug Delivery or Chelation
The molecule's hydrophilic and ionizable nature suggests potential utility in drug carrier systems or as a chelating ligand in metal complexation studies.
Benefits
✅ Zwitterionic Nature
Offers high buffering capacity with minimal interference in biological reactions due to its neutral net charge at certain pH levels.
✅ High Water Solubility
Freely soluble in aqueous solutions, allowing for easy incorporation into biochemical formulations.
✅ Low UV Absorbance
Suitable for use in UV-sensitive assays such as those involving proteins and nucleic acids.
✅ Chemical Stability
Stable under typical storage and lab conditions, enabling consistent performance in various applications.
✅ Environmentally Benign
Composed of biocompatible functional groups, making it environmentally and biologically safe for many applications.
Conclusion
3-Amino-1-propanesulfonic acid (CAS 3687-18-1) is a versatile zwitterionic compound offering stable buffering capacity, water solubility, and chemical robustness. It serves as an important intermediate in synthesis, a reliable buffer in life science research, and a potential component in advanced materials and formulations for pharmaceutical, biochemical, and industrial uses.

