Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of dexamethasone-17-acetate丨cas 1177-87-3 in China. Welcome to wholesale custom made chemical products at competitive price from our factory. For more cheap products, contact us now.
Specifications
| Grade: | USP 42 |
| Appearance: | White or almost white crystalline powder |
| Identification (IR, UV): | Complies with the standard |
| Specific Rotation: | +82 ~ +88° |
| Residue on ignition: | 0.1% max |
| Loss on drying: | 0.4% max |
| Heavy Metals: | 20 ppm max |
| Chromatographic purity: | |
| Individual Impurity: | 1.0% max |
| Total Impurity: | 2.0% max |
| Assay: | 97.0% - 102.0% |
| Residual solvents: | |
| Acetone: | 1000 ppm max |
Transport Information
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2937221000999 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Dry. 2-8℃ |
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Condition to Avoid |
Light. Oxidizing agents |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
1MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2013 |
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Stock |
Applications
1. Pharmaceutical Industry
Used as an active pharmaceutical ingredient (API) or intermediate in the production of topical, injectable, or oral corticosteroid medications.
Employed in formulations to treat conditions such as asthma, rheumatoid arthritis, allergic reactions, and dermatological inflammations.
The acetate ester form can enhance the drug's absorption and bioavailability in certain delivery routes.
2. Research & Development
Utilized in biochemical and pharmacological studies focused on corticosteroid mechanisms, receptor interactions, and anti-inflammatory effects.
Acts as a reference standard or starting material for synthesizing related corticosteroid derivatives.
Benefits
✔️ Potent Anti-inflammatory Activity
Exhibits strong glucocorticoid effects, effectively reducing inflammation and suppressing immune responses.
✔️ Improved Stability
The acetate ester enhances chemical stability compared to free dexamethasone, beneficial for longer shelf life and controlled release.
✔️ Versatile Formulation Options
Suitable for incorporation into various pharmaceutical forms, including creams, ointments, injectables, and tablets.
Conclusion
Dexamethasone-17-acetate is a valuable corticosteroid derivative widely used in pharmaceutical formulations for its potent anti-inflammatory and immunosuppressive effects. Its enhanced stability and versatility make it a preferred choice in the design of topical and systemic corticosteroid therapies.
