Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of minoxidil sulphate丨cas 83701-22-8 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Appearance: | White or off white crystal powder |
| Assay(HPLC): | 99% min |
| Identification: | IR similar to the reference standard |
| Odor: | Odourless |
| Solubility: | Soluble in water, propylene glycol; sparingly soluble in methanol |
| PH (3%): | 2.5–3.5 |
| Heavy metals: | 20 ppm max |
| Loss on drying: | 3% max |
| Residue on ignition: | 0.5% max |
| Organic volatile impurities: | |
| Methanol: | 3000 ppm max |
| Ethanol: | 5000 ppm max |
| Ethyl acetate: | 5000 ppm max |
Transport Information
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2933599099304 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
1MT/month |
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Frequency |
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Main Export Countries |
US, EU, India, Southeast Asia |
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Capacity/Batch |
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Experience |
Production since 2000 |
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Stock |
Applications
1. Hair Loss Treatment (Topical Use)
Primary application is in the treatment of androgenetic alopecia (male and female pattern baldness).
It enhances hair growth by prolonging the anagen (growth) phase of hair follicles.
Used in various topical hair regrowth formulations, either as a raw material or as a reference standard in pharmaceutical development.
2. Pharmaceutical R&D
Minoxidil sulfate is used in pharmacological studies to understand the mechanism of action of minoxidil at the molecular level.
Helps in formulation development for enhanced delivery and bioavailability in hair regrowth products.
3. Hypertension Research
As the active form of oral minoxidil (a systemic vasodilator), minoxidil sulfate has been studied for its role in vascular smooth muscle relaxation, although it is not directly administered in clinical practice for hypertension.
Benefits
✔️ More Potent Than Minoxidil
Minoxidil sulfate is 2–5 times more active than minoxidil itself in stimulating hair follicles.
It directly opens ATP-sensitive potassium channels, improving blood flow to the hair follicle and stimulating follicular activity.
✔️ Faster Onset of Action
Because it is the already-active metabolite, topical formulations containing minoxidil sulfate may act more rapidly in stimulating hair regrowth compared to minoxidil, which requires metabolic activation in the skin.
✔️ Improved Efficacy in Non-Responders
Some individuals have low sulfotransferase activity, meaning they cannot efficiently convert minoxidil into its active form. Using minoxidil sulfate directly may improve results in such users.
✔️ Better Solubility
It exhibits better water solubility than minoxidil, offering potential for more stable aqueous formulations.
Conclusion
Minoxidil sulphate is a potent vasodilator and hair growth stimulator, widely used in scientific research and formulation development for treating hair loss. While it offers enhanced efficacy, its formulation complexity and lower stability have limited its use in mass-market products. However, it remains an essential compound for researchers and pharmaceutical developers working on next-generation treatments for alopecia.
