Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of fluocinolone acetonide丨cas 67-73-2 in China. Welcome to wholesale custom made chemical products at competitive price from our factory. For more cheap products, contact us now.
Specifications
| Grade: | USP43 |
| Description: | White or almost white crystalline powder |
| Assay (HPLC, based on drying): | 97.5% ~ 102.0% |
| Identification: | A: IR; B: HPLC |
| Solubility: | Soluble in methanol, slightly soluble in ether and in chloroform, insoluble in water |
| Specific rotation: | +98° ~ +108° |
| Loss on drying: | 1.0% max |
| Organic impurity (HPLC): | |
| Any individual impurity: | 1.0% max |
| Total impurities: | 2.5% max |
| Residual solvents: | |
| Dichloromethane: | 600 ppm max |
| Methanol: | 3000 ppm max |
| Acetone: | 5000 ppm max |
| Ethanol: | 5000 ppm max |
Transport Information
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2937229000999 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
100kg/year |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2018 |
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Stock |
Applications
1. Dermatology
Primary use: Treatment of inflammatory skin disorders, such as:
Eczema
Psoriasis
Dermatitis
Applied topically in creams, ointments, lotions, or gels to reduce inflammation, redness, and itching.
2. Ophthalmology
Formulated into eye drops or implants (e.g., Retisert®) to manage:
Chronic non-infectious uveitis
Macular edema
Helps reduce intraocular inflammation and preserve vision.
3. Otic Treatments
Combined with antibiotics (e.g., fluocinolone + ciprofloxacin) for:
Ear infections
Otitis externa
Reduces inflammation and discomfort in ear canal infections.
4. Dental and Oral Applications
Used in low-dose oral gels or pastes for treating:
Oral lichen planus
Aphthous ulcers
Reduces swelling and pain in the mouth or gums.
5. Cosmetic Formulations
Occasionally incorporated in specialized skin care treatments for:
Pigmentation disorders
Seborrheic dermatitis
Benefits
Potent Anti-inflammatory Action: Inhibits synthesis of pro-inflammatory compounds like prostaglandins and leukotrienes.
Local Application: Reduces systemic exposure and side effects when applied topically.
Long-lasting Effects: Especially in intraocular implants, providing extended anti-inflammatory relief.
Combination Therapy: Often used with antibiotics or antifungals for dual-action treatment.
Conclusion
Fluocinolone Acetonide (CAS 67-73-2) is a widely used corticosteroid known for its strong anti-inflammatory and antipruritic effects. Its applications span dermatological, ophthalmic, otic, dental, and cosmetic treatments, offering targeted relief from inflammation with minimal systemic side effects when used appropriately. Its broad utility and effectiveness make it a critical active pharmaceutical ingredient in both prescription and over-the-counter medications.
