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Specifications of Cefradine丨CAS 38821-53-3
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Grade: |
CP2015 |
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Appearance: |
White to off-white crystalline powder |
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Assay (dried base): |
90% min |
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Specific rotation: |
+80° ～ +90° |
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Identification: |
HPLC + IR conforms |
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Crystallinity: |
Conforms |
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pH: |
3.5 - 6.0 |
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Character of solution: |
#1 max |
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Color: |
Y5# or YG5# max |
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Related substances: |
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7-ADCA: |
1.0% max |
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Dihydrophenylglycine: |
1.0% max |
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Single impurity: |
2.0% max |
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Total impurities: |
2.5% max |
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Cefradine polymer: |
0.05% max |
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2-naphthol: |
0.05% max |
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Water: |
6.0% max |
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Residual on ignition: |
0.2% max |
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Heavy metals: |
20 ppm max |
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N,N-dimethylformamide: |
0.088% max |
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Dichloromethane: |
0.06% max |
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Acetone: |
0.5% max |
Transport Information of Cefradine丨CAS 38821-53-3
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2941905400999 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Dry. 2-8℃ |
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Condition to Avoid |
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. |
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Package |
Manufacturing Information of Cefradine丨CAS 38821-53-3
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Parameter |
Specification |
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Capacity |
10MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2007 |
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Stock |
Overview
Cefradine丨CAS 38821-53-3 is a β-lactam antibiotic belonging to the cephalosporin family. It is a first-generation cephalosporin known for its broad-spectrum activity against Gram-positive and some Gram-negative bacteria. It is widely used in clinical medicine to treat various bacterial infections.
Applications
1. Treatment of Bacterial Infections
Respiratory Tract Infections:
Effective against streptococci, staphylococci, and other pathogens causing pneumonia, bronchitis, tonsillitis, and pharyngitis.
Skin and Soft Tissue Infections:
Used for cellulitis, abscesses, and wound infections caused by susceptible bacteria.
Urinary Tract Infections (UTIs):
Treats uncomplicated UTIs caused by E. coli and other susceptible organisms.
Bone and Joint Infections:
Sometimes employed for osteomyelitis and septic arthritis under medical supervision.
2. Surgical Prophylaxis
Cefradine is used preoperatively to prevent postoperative infections due to its broad-spectrum efficacy and favorable safety profile.
3. Veterinary Medicine
Employed in animals to treat bacterial infections similar to human indications, enhancing animal health and productivity.
Benefits
1. Broad-Spectrum Antibacterial Activity
Active against many Gram-positive cocci and some Gram-negative rods, offering versatile clinical utility.
2. Oral Bioavailability
Available in oral formulations, facilitating outpatient treatment and better patient compliance.
3. Safety Profile
Generally well-tolerated with a low incidence of adverse effects.
Less likely to cause severe allergic reactions compared to some other β-lactams, though caution is required in penicillin-allergic patients.
4. Rapid Bactericidal Action
Quickly inhibits bacterial cell wall synthesis, leading to bacterial death and symptom resolution.
Conclusion
Cefradine丨CAS 38821-53-3 is an effective first-generation cephalosporin antibiotic widely used for treating a variety of bacterial infections. Its broad-spectrum activity, oral availability, and favorable safety profile make it a valuable agent in both human and veterinary medicine. Its rapid bactericidal effect contributes to improved clinical outcomes and infection control.
