Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of ethyl n-acetyl-l-tyrosinate hydrate丨cas 36546-50-6 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Appearance | White powder |
| Purity (HPLC) | 98% min |
| Melting Point | 73℃ to 83℃ |
| Specific Rotation [α]20D | +23° ±2° (C=1 in EtOH) |
| Clarity of solution | 0.3 gram in 6 ml EtOAc clear solution |
| Water Content (K.F.) | 8% max |
| Loss on drying | 1% max (35℃, 2h) |
| IR Spectrum | In accordance with the structure |
| Mass Spectrum | In accordance with the structure |
| NMR Spectrum | In accordance with the structure |
Applications
Ethyl N-acetyl-L-tyrosinate hydrate is primarily used as an intermediate in pharmaceutical and biochemical research. Its structure, featuring both an acetyl-protected amino group and an esterified tyrosine residue, makes it valuable for peptide synthesis and the preparation of tyrosine-derived derivatives. It is commonly applied in the development of enzyme inhibitors, neurotransmitter analogs, and other biologically active compounds. Researchers utilize it in studying metabolic pathways involving tyrosine and its derivatives, as well as in the synthesis of small molecule drugs and prodrugs. Additionally, it can serve as a building block for designing peptides with improved stability, solubility, or pharmacokinetic properties.
Benefits
The compound provides several benefits in chemical and pharmaceutical synthesis. The acetyl protection of the amino group prevents unwanted side reactions during multi-step synthesis, allowing for selective reactions at the carboxyl or phenolic hydroxyl groups. Its ethyl ester functionality increases solubility in organic solvents and facilitates efficient coupling reactions, which enhances overall synthetic efficiency. The hydrate form offers improved stability and ease of handling compared to anhydrous derivatives. Overall, Ethyl N-acetyl-L-tyrosinate hydrate enables precise modification of tyrosine residues, supporting the design of high-purity compounds for research and drug development.
Conclusion
Ethyl N-acetyl-L-tyrosinate hydrate is a versatile and valuable intermediate in pharmaceutical and biochemical synthesis. Its protected amino acid structure allows for selective functionalization, streamlined peptide synthesis, and the creation of tyrosine-derived bioactive molecules. By combining stability, solubility, and reactivity, it serves as a reliable building block for researchers developing drugs, probes, and other biologically relevant compounds.
