Gamma-Cyclodextrin丨CAS 17465-86-0

Gamma-Cyclodextrin丨CAS 17465-86-0
Product Introduction:
Catalog No.: SS107219
CAS No.: 17465-86-0
Content: 98%min
Product Name: gamma-Cyclodextrin
Molecular Formula: C48H80O40
Molecular Weight: 1297.12
Synonym(s): Cyclooctapentylose
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Technical Parameters
Description

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Specifications

Appearance:

White to off-white powder

Content:

98% min

Residue on ignition:

0.1% max

Reducing sugar:

0.5% max

Heavy metals:

5 ppm max

Pb:

0.5 ppm max

As:

1.3 ppm max

Residue on solvents:

20 ppm max

Water content:

11.0% max

Specific rotation:

+173° to +180°

Total number of bacterial colony:

1000 CFU/g max

Coliform group:

40 MPN/g max

Mold:

25 CFU/g max

Yeast:

25 CFU/g max

Pathogens in 25g:

Absence

 

 

Transport Information

Parameter

Specification

UN Number

 

Class

 

Packing Group

 

H.S. Code

3505100000302

Stability & Reactivity

The product is chemically stable under standard ambient conditions.

Storage

Tightly closed. Store in a closed, dry, ventilated place

Condition to Avoid

 

Package

 

 

Manufacturing Information

Parameter

Specification

Capacity

1MT/month

Frequency

 

Main Export Countries

 

Capacity/Batch

 

Experience

Production since 2015

Stock

 

 

 

Overview

 

gamma-Cyclodextrin丨CAS 17465-86-0 is a cyclic oligosaccharide composed of eight α-D-glucopyranose units linked by α-1,4-glycosidic bonds. It is part of the cyclodextrin family, which includes α-, β-, and γ-cyclodextrins, differing by the number of glucose units (6, 7, and 8 respectively). Among these, γ-CD has the largest internal cavity, making it ideal for forming inclusion complexes with larger or more hydrophobic guest molecules.

 

Applications

 

1. Pharmaceuticals

Drug Solubilizer & Stabilizer: Improves solubility and bioavailability of poorly water-soluble drugs through inclusion complexation.

Controlled Release Agent: Provides sustained or targeted drug delivery, especially for oral, nasal, and injectable formulations.

Taste Masking: Encapsulates bitter or unpleasant-tasting drugs.

Stabilization: Enhances thermal and photostability of drugs and biologics (e.g., peptides, steroids, vitamins).

2. Food Industry

Flavor Encapsulation: Traps volatile aroma and flavor molecules, preventing degradation and extending shelf life.

Cholesterol Removal: Used in dairy and egg processing to selectively remove cholesterol without affecting taste or nutrition.

Carrier for Nutrients: Improves dispersibility and stability of fat-soluble vitamins (e.g., A, D, E, K) and antioxidants.

Dietary Fiber & Prebiotic: Considered safe and digestible in small amounts, supporting gut health.

3. Cosmetics & Personal Care

Fragrance Stabilization: Protects and prolongs the release of volatile fragrance ingredients.

Active Ingredient Delivery: Enhances the penetration and efficacy of active cosmetic agents like retinoids or botanical extracts.

Improved Texture: Can help control viscosity and reduce stickiness in formulations.

4. Environmental & Industrial Uses

Pollutant Removal: Forms complexes with organic pollutants, pesticides, and heavy metals in environmental remediation.

Green Solvent System: Used in catalysis and chemical separations due to its biodegradable, non-toxic profile.

Textile & Polymer Applications: Used in smart materials to enable controlled release of fragrances or antimicrobial agents.

 

Benefits

 

Feature

Benefit

Large Cavity Size

Can accommodate larger molecules than α- or β-cyclodextrins.

High Aqueous Solubility

Greater than β-CD, making it suitable for water-based systems.

Low Toxicity and Biodegradability

Safe for human consumption (GRAS in the U.S. for some uses) and environmentally friendly.

Improved Bioavailability

Enables better absorption of lipophilic drugs or nutrients.

Versatility

Useful in a wide range of industries, from medicine to cosmetics to food science.

 

Conclusion

 

gamma-Cyclodextrin丨CAS 17465-86-0 is a biocompatible, water-soluble, and high-capacity encapsulating agent that supports applications across pharmaceuticals, food technology, cosmetics, and environmental science. Its large cavity size and excellent safety profile make it a valuable ingredient for improving the performance, safety, and stability of a wide range of products.

 

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