Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of sodium sulfadiazine丨cas 547-32-0 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications of Sodium sulfadiazine丨CAS 547-32-0
|
Item |
Specification |
|
Grade |
USP43 |
|
Appearance |
White or almost white crystalline or powder |
|
Assay (calculated on the dried basis) |
99% to 100.5% |
|
Identification A |
The infrared absorption spectrum concordant with the spectrum of sulfadiazine CRS |
|
Identification B |
Test for sodium |
|
Solubility |
Freely soluble in water, slightly soluble in alcohol |
|
Heavy Metals |
10 ppm max |
|
Melting Range |
250°C to 254°C |
|
Clarity of the Solution |
Clear |
|
pH |
9.6 to 10.5 |
|
Selenium |
30 ppm max |
|
Loss on Drying |
0.5% max |
Transport Information of Sodium sulfadiazine丨CAS 547-32-0
|
Parameter |
Specification |
|
UN Number |
3077 |
|
Class |
|
|
Packing Group |
|
|
H.S. Code |
2935900090 |
|
Stability & Reactivity |
The product is chemically stable under standard ambient conditions (room temperature). |
|
Storage |
Tightly closed. Store in a closed, dry, ventilated place |
|
Condition to Avoid |
|
|
Package |
Overview
Sodium sulfadiazine丨CAS 547-32-0 is the sodium salt of sulfadiazine, a sulfonamide antibiotic. It is used for its broad-spectrum antibacterial activity, particularly in the treatment and prevention of bacterial infections in humans and animals. It is commonly used systemically or in topical formulations, especially when water solubility is needed for injections or high-dose therapies.
Applications of Sodium sulfadiazine丨CAS 547-32-0
1. Human Medicine
a. Antibacterial Agent
● Sodium sulfadiazine丨CAS 547-32-0 is effective against a wide range of Gram-positive and Gram-negative bacteria, especially Streptococcus, E. coli, and some strains of Haemophilus.
● Often used in urinary tract infections, respiratory infections, and toxoplasmosis when combined with pyrimethamine.
b. Alternative to Silver Sulfadiazine
● In certain formulations, sodium sulfadiazine may be used where silver-based creams are contraindicated.
● Also explored in systemic infections requiring soluble sulfonamide forms.
2. Veterinary Medicine
● Used to treat bacterial infections in livestock (e.g., pigs, cattle, poultry) and companion animals.
● Often included in feed additives or injectable solutions for treating enteritis, pneumonia, and wound infections in animals.
3. Pharmaceutical Formulations
● Acts as an active pharmaceutical ingredient (API) in the production of:
oInjectable antibiotics
oOral sulfonamide tablets
oEye drops and topical antimicrobial preparations
Benefits of Sodium sulfadiazine丨CAS 547-32-0
√ Broad-Spectrum Antibacterial Activity
● Effective against a wide variety of bacterial pathogens by inhibiting folic acid synthesis, an essential process in bacterial metabolism.
√ Water-Soluble Salt Form
● The sodium salt improves bioavailability and allows parenteral (injectable) administration, particularly in patients who cannot take oral medication.
√ Useful in Combination Therapy
● Used with pyrimethamine to treat toxoplasmosis and malaria, taking advantage of synergistic inhibition of microbial folate pathways.
√ Cost-Effective and Widely Available
● Generic and affordable, making it a staple antibiotic in resource-limited settings or veterinary practices.
√ Veterinary and Agricultural Uses
● Helps maintain livestock health and prevent economic losses due to bacterial outbreaks in animal farming.
Conclusion
Sodium sulfadiazine丨CAS 547-32-0 is a potent sulfonamide antibiotic valued for its water solubility, broad-spectrum activity, and effectiveness in systemic and topical applications. It remains a useful and cost-effective solution for both human and veterinary medicine, particularly in treating bacterial infections and protozoal diseases such as toxoplasmosis.
