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Specifications of Allopurinol丨315-30-0
|
Property |
Specification |
|
Appearance |
White crystalline powder |
|
Assay |
98.0~102% |
|
Loss on Drying |
0.5% max |
|
Sulphated Ash |
0.1% max |
Transport Information of Allopurinol丨315-30-0
|
Parameter |
Specification |
|
UN Number |
2811 |
|
Class |
|
|
Packing Group |
|
|
H.S. Code |
2933990099306 |
|
Stability & Reactivity |
Stable |
|
Storage |
Tightly closed. Store in a closed, dry, ventilated place |
|
Condition to Avoid |
formation of dust and aerosols |
|
Package |
Introduction
Allopurinol丨315-30-0 is a xanthine oxidase inhibitor primarily used to treat gout and hyperuricemia (high levels of uric acid in the blood). It is an essential pharmaceutical compound that helps prevent kidney stones, uric acid-related complications, and certain types of chemotherapy-induced hyperuricemia.
Applications of Allopurinol丨315-30-0
1. Treatment of Gout and Hyperuricemia
Primary Medication for Gout:
Reduces uric acid production in the body, preventing gout attacks and joint inflammation.
Long-Term Management of Chronic Gout:
Used as a preventive therapy to avoid recurrent gout flares.
2. Prevention of Kidney Stones and Renal Complications
Prevents Uric Acid Kidney Stones:
Lowers uric acid levels, reducing the risk of urinary tract stone formation.
Used in Patients with Chronic Kidney Disease (CKD):
Helps manage high uric acid levels in CKD patients to prevent kidney damage.
3. Cancer and Chemotherapy Support
Reduces Chemotherapy-Induced Hyperuricemia:
Prevents complications caused by tumor lysis syndrome (TLS), which can occur during aggressive cancer treatments.
4. Cardiovascular and Neurological Applications (Investigational Use)
Potential Cardiovascular Benefits:
May help in reducing oxidative stress and improving outcomes in heart failure and hypertension.
Neurological Research:
Being studied for its role in neuroprotection in conditions like Parkinson's disease and stroke.
Benefits of Allopurinol丨315-30-0
1. Effective in Uric Acid Reduction
● Lowers uric acid production, preventing gout attacks and kidney stones.
2. Prevents Severe Uric Acid Complications
● Protects patients undergoing chemotherapy or kidney-related conditions.
3. Long-Term Gout Management with Fewer Side Effects
● Safe for chronic use with proper medical supervision.
4. Potential Expanding Therapeutic Use
● Being investigated for cardiovascular and neurological disorders.
Conclusion
Allopurinol丨315-30-0 is a critical medication for managing gout, hyperuricemia, and kidney stones. Its ability to inhibit xanthine oxidase and lower uric acid levels makes it a key drug in rheumatology, oncology, and nephrology. Additionally, ongoing research suggests its potential in cardiovascular and neurological health.
