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Specifications
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Grade: |
USP Grade |
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Appearance: |
White crystalline powder |
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Assay (Calculated on the dried basis): |
98.0% ~ 102.0% |
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Platinum content (Calculated on the dried basis): |
52.0% ~ 53.0% |
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Identification: |
Spectrum sample should be consistent with spectrum of reference standard. |
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pH: |
5.0 ~ 7.0 |
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Loss on drying: |
0.5% max |
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Transmittance: |
97% min |
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Water-insoluble matter: |
0.5% max |
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1.1-Cyclobutanedicarboxylic acid: |
0.5% max |
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Related substances: |
Cisplatin: 0.25% max |
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Residual solvent: |
Ethanol: 500 ppm max |
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Bacterial endotoxins: |
0.54 EU/mg max |
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Crystalfinity: |
Meets the requirements |
Transport Information
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2843900090 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Keep container tightly closed. Store in a cool and shaded area. Recommended storage temperature 2 - 8 °C |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
200kg/year |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2012 |
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Stock |
Carboplatin丨CAS 41575-94-4 is a platinum-based chemotherapy drug widely used for treating various cancers. It is a second-generation platinum compound, developed as a less toxic alternative to cisplatin while maintaining anticancer efficacy. Carboplatin functions by crosslinking DNA, thereby interfering with DNA replication and transcription, which leads to apoptosis (cell death) in rapidly dividing cancer cells.
Applications
1. Cancer Chemotherapy
Carboplatin is used as a first-line or adjuvant therapy in treating a variety of cancers, including:
Ovarian cancer
Lung cancer (especially non-small cell lung cancer)
Head and neck cancers
Testicular cancer
Bladder cancer
2. Combination Therapy
Frequently administered in combination with other chemotherapeutic agents such as paclitaxel or gemcitabine to enhance treatment efficacy.
Used in neoadjuvant and adjuvant settings to shrink tumors before surgery or eliminate residual disease post-surgery.
3. Research and Development
Carboplatin丨CAS 41575-94-4 serves as a model drug in research on:
Platinum drug resistance mechanisms
DNA damage and repair pathways
Development of novel platinum-based analogs with improved efficacy and reduced toxicity.
Benefits and Advantages
Reduced toxicity compared to cisplatin, especially less nephrotoxicity, neurotoxicity, and gastrointestinal side effects.
Improved patient tolerance, allowing for higher dosing or combination regimens.
Effective across a broad range of tumor types.
Water-soluble and relatively stable, facilitating intravenous administration.
Summary
Carboplatin丨CAS 41575-94-4 is a cornerstone platinum-based anticancer drug widely used to treat multiple malignancies due to its effective DNA crosslinking activity with a comparatively favorable toxicity profile. Its role in combination chemotherapy and ongoing research into resistance mechanisms underscores its importance in oncology.
