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Specifications
| Grade | Food grade |
| Appearance | White to off-white powder |
| Purity (HPLC) | 98.0% min |
| Identification | 1H NMR confirms to structure |
| Loss on drying | 0.5% max |
| Chloridion | 11.2% to 13.2% |
| Residue on ignition | 0.5% max |
| Heavy metals | 10 ppm max |
| Pb (Lead) | 0.5 ppm max |
| Cd (Cadmium) | 2.5 ppm max |
| Hg (Mercury) | 1.5 ppm max |
| As (Arsenic) | 0.15 ppm max |
| Ethanol | 5000 ppm max |
| Methanol | 3000 ppm max |
| Acetone | 5000 ppm max |
Applications
Nicotinamide riboside chloride (NR) is a naturally occurring compound that serves as a precursor to nicotinamide adenine dinucleotide (NAD+), an essential coenzyme involved in various cellular processes. NR is increasingly used in the nutritional and supplement industries due to its potential to boost NAD+ levels in the body. This makes it a popular ingredient in anti-aging products, energy supplements, and products aimed at improving cellular health. By increasing NAD+ levels, NR has been associated with enhanced mitochondrial function, improved metabolism, and better DNA repair mechanisms. Additionally, NR is being explored for its therapeutic potential in age-related diseases, neurodegenerative conditions like Alzheimer's, and metabolic disorders such as type 2 diabetes. Beyond supplements, NR is also being studied in clinical trials for its potential role in longevity and improving overall healthspan.
Benefits
The primary benefits of nicotinamide riboside chloride stem from its ability to boost NAD+ levels in the body. NAD+ is crucial for energy production, DNA repair, and maintaining mitochondrial function, which all naturally decline with age. By increasing NAD+ levels, NR may help improve cellular energy production, support healthy aging, and enhance metabolic processes. Research has also shown that NR may promote improved insulin sensitivity and aid in the management of metabolic diseases, such as obesity and type 2 diabetes. Furthermore, because NAD+ plays a critical role in regulating sirtuins (proteins involved in aging and stress response), NR's ability to increase NAD+ is linked to potential longevity benefits, improving brain function and protecting against age-related diseases like Alzheimer's and Parkinson's. Additionally, NR has shown promise in improving muscle function and endurance, potentially offering benefits for physical performance and recovery.
Conclusion
Nicotinamide riboside chloride (CAS 23111-00-4) is a promising compound with significant applications in the health and wellness industry. Its ability to increase NAD+ levels makes it beneficial for improving mitochondrial function, metabolism, and overall cellular health. As a supplement, NR is linked to potential anti-aging effects, improved metabolic health, and better brain and muscle function. Its growing use in clinical research underscores its potential in treating age-related diseases and enhancing overall healthspan. While further studies are needed to fully understand its long-term effects, the current evidence supports its value as a nutritional supplement aimed at boosting energy, improving metabolic health, and promoting longevity.
