D-Luciferin Potassium Salt丨CAS 115144-35-9

D-Luciferin Potassium Salt丨CAS 115144-35-9
Product Introduction:
Catalog No.: SS104591
CAS No.: 115144-35-9
Purity(HPLC): 99% min
Product Name: D-Luciferin potassium salt
Molecular Formula: C11H7KN2O3S2
Molecular Weight: 318.4
Synonym(s): Potassium (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate
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Technical Parameters
Description

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Specifications

 

Appearance: Light yellow to yellow powder
Purity (HPLC): 99% min
Solubility: 30mg/ml min
Loss on drying: 1.0% max
MS: Conforms to structure
HNMR: Conforms to structure

 

Transport Information

 

Parameter

Specification

UN Number

 

Class

 

Packing Group

 

H.S. Code

2934200090999

Stability & Reactivity

The product is chemically stable under standard ambient conditions.

Storage

Handle and store under inert gas. Store in the dark. Moisture sensitive. Recommended storage temperature: -20°C

Condition to Avoid

 

Package

 

 

Manufacturing Information

 

Parameter

Specification

Capacity

1kg/year

Frequency

 

Main Export Countries

 

Capacity/Batch

 

Experience

Production since 2021

Stock

 

 

 

 

Applications

 

1. In Vivo and In Vitro Bioluminescent Imaging

Widely used in live animal imaging to monitor biological processes such as tumor growth, infection progression, and gene expression.

The potassium salt form offers improved solubility and stability, ideal for intravenous or intraperitoneal injections in animal models.

2. Reporter Gene Assays

Serves as a substrate in luciferase-based reporter systems for studying gene regulation, cell signaling, and transcriptional activity.

The enhanced solubility improves assay reproducibility and sensitivity.

3. High-Throughput Screening

Applied in drug discovery platforms to assess enzyme activity, cell viability, and compound effects with bioluminescent readouts.

4. Biosensor Development

Used in biosensors detecting ATP or other analytes where bioluminescence indicates target presence or enzymatic activity.

 

Benefits

 

1. Enhanced Water Solubility

Potassium salt form dissolves readily in aqueous buffers, facilitating consistent dosing and improved bioavailability.

2. Improved Stability

More chemically stable than free acid, allowing for longer shelf life and better handling during experiments.

3. High Sensitivity

Retains the high sensitivity and specificity of the D-Luciferin-luciferase reaction, producing bright bioluminescent signals with low background noise.

4. Non-Invasive Real-Time Monitoring

Supports non-invasive, longitudinal studies of biological events in living organisms, enabling dynamic tracking.

5. Versatile Compatibility

Compatible with various luciferase enzymes and cell types across research models.

 

Conclusion

 

D-Luciferin potassium salt (CAS 115144-35-9) is a water-soluble, stable form of the bioluminescent substrate D-Luciferin. It is widely used for bioluminescent imaging, gene reporter assays, drug screening, and biosensor applications. Its enhanced solubility and stability make it particularly useful for in vivo animal studies and high-throughput assays, providing researchers with reliable and sensitive tools for studying biological processes in real time.

 

 

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