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Specifications
| Appearance: | White to off-white powder |
| Purity (HPLC): | 98% min |
| Solubility: | 0.3g transparent solution dissolved in 2 milliliters of aqueous solution |
| Loss on drying: | 1.0% max (105°C, 2 h) |
| Specific rotation: | +50~+54° (c=1 in H₂O) |
| MS: | Consistent with structure |
| NMR: | Consistent with structure |
Applications
1. Biochemical Research
L-Methionine sulfoxide is used to study oxidative stress and protein oxidation. Researchers utilize it to understand the mechanisms of protein damage and repair, shedding light on cellular responses to oxidative stress.
2. Peptide Synthesis
It is employed to introduce oxidation sites into peptides, useful for studying the effects of oxidation on peptide structure and function. This helps in designing more stable therapeutic peptides.
3. Biotechnology and Antimicrobial Strategies
The involvement of L-methionine sulfoxide in bacterial oxidative stress defense systems can inform the development of novel antimicrobial strategies targeting bacterial stress responses.
4. Nutritional Studies
Studies show that substituting L-methionine with L-methionine sulfoxide in diets can influence weight gain in animals, suggesting potential applications in nutrition and metabolism research.
Benefits
Antioxidant Defense: Methionine sulfoxide reductases repair oxidized methionine residues, protecting proteins from oxidative damage.
Aging and Longevity: Enhanced Msr activity correlates with longer lifespan in certain organisms, highlighting its role in aging research.
Disease Prevention: Maintaining protein function through oxidation repair may help prevent age-related diseases linked to protein oxidation.
Therapeutic Development: Insights into L-methionine sulfoxide's role in protein oxidation and repair support the development of treatments targeting oxidative stress-related disorders.
Conclusion
L-Methionine sulfoxide is essential in understanding oxidative stress and protein function. Its applications in biochemical research, biotechnology, and therapeutic development highlight its importance in mitigating oxidative damage and maintaining cellular health.
