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Specifications
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Appearance: |
White crystalline granule |
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Identity by MS: |
178.21 ± 1 |
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Solubility: |
Soluble in water |
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Peptide purity (By HPLC): |
95.0% min |
Transport Information
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2924199090306 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Recommended storage temperature: -20 °C |
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Condition to Avoid |
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Package |
Cys-Gly丨CAS 19246-18-5 is a dipeptide composed of the amino acids cysteine and glycine, linked by a peptide bond. It is a significant biological molecule often found as a breakdown product of glutathione (GSH), one of the most important intracellular antioxidants. Cys-Gly plays important roles in cellular redox balance, detoxification, and metabolism.
Applications
1. Biological and Biochemical Research
Glutathione metabolism: Cys-Gly is an intermediate in the degradation and recycling of glutathione.
Used in studies related to:
Oxidative stress and antioxidant defense mechanisms.
Enzymatic pathways involving gamma-glutamyltransferase (GGT).
Acts as a model substrate or standard for enzymes that cleave or modify glutathione and related peptides.
2. Pharmaceutical and Clinical Research
Investigated for its potential in modulating oxidative damage in diseases such as:
Neurodegenerative disorders
Cancer
Inflammatory conditions
Its role in cellular detoxification makes it a candidate for studying drug metabolism and toxicity.
3. Nutraceutical and Supplement Industry
As a metabolite of glutathione, it is explored for potential use in nutritional supplements aimed at boosting antioxidant capacity.
May support detoxification pathways and improve cellular health.
4. Analytical Standards
Used as a reference compound in HPLC, mass spectrometry, and other analytical methods for detecting and quantifying glutathione metabolites in biological samples.
5. Chemical Synthesis
Used as a building block for peptide synthesis and in the preparation of modified peptides for biological studies.
Benefits and Properties
Antioxidant precursor: Helps regenerate reduced glutathione pools.
Biocompatible: Naturally occurring, low toxicity.
Water soluble: Easily handled in aqueous solutions for biochemical assays.
Versatile intermediate: Useful in enzymatic and chemical synthesis studies.
Summary
Cys-Gly丨CAS 19246-18-5 is a biologically important dipeptide, central to glutathione metabolism and cellular antioxidant defense. It serves crucial roles in biochemical research, pharmaceutical studies, and as a standard in analytical techniques. Its natural occurrence and biological relevance make it valuable for investigating oxidative stress-related diseases and metabolic pathways.
