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Specifications of D-Proline丨344-25-2
|
Parameter |
Specification |
|
Appearance |
White crystals or crystalline powder |
|
Assay |
98.5% to 101.0% |
|
Specific Rotation [α]D20 |
+83.5° to +86.5° |
|
Chloride (Cl) |
0.020% max |
|
Ammonium (NH4) |
0.02% max |
|
Sulfate (SO4) |
0.020% max |
|
Heavy Metals (Pb) |
10 ppm max |
|
Arsenic (As2O3) |
2 ppm max |
|
Other Amino Acids |
0.5% max |
|
Loss on Drying |
0.50% max |
|
Residue on Ignition |
0.30% max |
|
Isomer Purity |
0.3% max |
|
pH |
5.9 to 6.9 |
Applications of D-Proline丨344-25-2
Pharmaceutical Industry
D-Proline丨344-25-2 is widely used in the pharmaceutical industry as a chiral building block for the synthesis of various drugs. It plays a crucial role in the production of peptide-based pharmaceuticals and is a key component in drug formulations targeting neurological, cardiovascular, and metabolic disorders.
Peptide and Protein Synthesis
As a non-essential amino acid, D-Proline is used in the synthesis of peptides and proteins, particularly in designing peptide-based drugs and biologics. It contributes to the stability and folding of peptide structures, making it valuable in biochemical research and drug development.
Chemical and Industrial Applications
D-Proline is used as an intermediate in organic synthesis, particularly in the preparation of chiral compounds and asymmetric synthesis. It is an important reagent in the production of fine chemicals, agrochemicals, and pharmaceutical intermediates.
Biochemical Research and Enzyme Studies
In biochemical studies, D-Proline is used to investigate enzyme activity and protein interactions. It is essential in research related to proline metabolism, protein folding, and molecular chaperones.
Benefits of D-Proline丨344-25-2
Chirality in Drug Development
D-Proline provides a chiral environment in pharmaceutical synthesis, enabling the production of enantiomerically pure drugs. This enhances drug efficacy and reduces potential side effects associated with racemic mixtures.
Enhances Peptide and Protein Stability
Due to its rigid cyclic structure, D-Proline helps maintain the stability of peptides and proteins, making it valuable in drug formulation and biochemical applications.
Versatile Applications in Chemical Synthesis
D-Proline serves as a key intermediate in various chemical reactions, supporting the production of bioactive molecules and specialty chemicals.
Potential Role in Neurological Research
Studies suggest that D-Proline and its derivatives may have neuroprotective properties, contributing to research on cognitive function and neurodegenerative diseases.
Conclusion
D-Proline丨344-25-2 is an essential chiral amino acid with significant applications in pharmaceuticals, peptide synthesis, and biochemical research. Its role in drug development, chemical synthesis, and enzyme studies makes it a valuable compound in scientific and industrial fields. Ongoing research continues to explore its potential benefits in neurological and metabolic health.
