2-Aminonicotinic Acid丨CAS 5345-47-1

1. Pharmaceutical Intermediate

Commonly used in the synthesis of active pharmaceutical ingredients (APIs).

Serves as a building block for various heterocyclic compounds.

Used in drug discovery for anti-inflammatory, antibacterial, or anticancer agents due to its pyridine-based structure.

2. Ligand in Coordination Chemistry

Acts as a bidentate ligand, coordinating through the amino and carboxylic groups.

Used to form metal-organic complexes, especially with transition metals (e.g., Cu, Fe, Zn), which are studied for catalytic, magnetic, or biological properties.

3. Organic Synthesis

Useful intermediate for synthesizing:

Pyridine derivatives

Heterocyclic compounds

Functionalized azo dyes or polymers

4. Agrochemical Research

Investigated as a precursor for synthesizing biologically active compounds such as plant growth regulators, fungicides, or herbicides.

5. Analytical Chemistry

May be employed in the development of complexometric titrants or chelating agents for metal ion detection or separation.

Dual Functional Groups: Its amino and carboxylic acid moieties provide multiple points of reactivity for chemical derivatization.

Good Water Solubility: Facilitates its use in aqueous-based synthesis and biological testing.

Versatility: Widely applicable in drug design, materials science, and coordination chemistry.

Structural Simplicity: Makes it a suitable core for modifications in structure-activity relationship (SAR) studies.