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Specifications
| Appearance: | White or almost white powder | ||||||
| Solubility: | Soluble in water | ||||||
| Water Content (Karl Fischer): | 10.0% max | ||||||
| Acetic Acid (By HPLC): | 4.0% - 15.0% | ||||||
| Acetic acid and water: | 20.0% max | ||||||
| Peptide Purity (By HPLC): | 95.0% min | ||||||
| Related Substance (By HPLC): |
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| Organic Solvent Residue: |
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Applications
1. Treatment of Osteoporosis
Used to reduce bone resorption by inhibiting osteoclast-mediated bone breakdown.
Helps increase bone mineral density, decreasing the risk of fractures.
Available in injectable, nasal spray, and other formulations.
2. Paget's Disease of Bone
Effective in normalizing bone remodeling in Paget's disease by suppressing excessive bone turnover.
3. Hypercalcemia
Used to treat hypercalcemia of malignancy or other conditions with elevated blood calcium.
Lowers serum calcium levels by reducing bone resorption and increasing renal calcium excretion.
4. Bone Pain Management
Provides relief in bone pain associated with osteoporosis and metastatic bone disease, possibly through modulation of nerve activity.
Benefits
Potent Anti-Resorptive Agent: Salmon calcitonin is more effective and longer-lasting than human calcitonin.
Rapid Action: Quickly lowers elevated calcium levels and reduces bone turnover.
Multiple Delivery Forms: Available as nasal spray, injection, or subcutaneous forms for flexible use.
Well-Studied: Established safety and efficacy profile over decades of clinical use.
Adjunct Therapy: Often used alongside calcium and vitamin D supplements to optimize bone health.
Conclusion
Calcitonin Salmon (CAS 47931-85-1) is a therapeutic peptide widely used to manage osteoporosis, Paget's disease, hypercalcemia, and bone pain. Its potent inhibition of bone resorption and favorable pharmacokinetics make it a valuable agent in bone health management. Available in various formulations, it offers effective and flexible treatment options for patients with metabolic bone disorders.

