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Specifications
| Appearance: | White or off-white powder | ||||||||||||||||
| Purity (HPLC): | 98.0% min. | ||||||||||||||||
| Solubility: | Sparingly soluble in MeOH, soluble in water and 1% acetate acid | ||||||||||||||||
| HPLC: | The principal peak in the chromatogram obtained with the test solution is similar in retention time to principal peak in the chromatogram obtained with the reference solution. | ||||||||||||||||
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| MS: | 1167.3 ± 1.0 | ||||||||||||||||
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| Specific Optical Rotation: | -46.0° to -56.0° (anhydrous and acetic acid free substance) | ||||||||||||||||
| Assay: | 97.0% - 103.0% (anhydrous and acetic acid free substance) | ||||||||||||||||
| Bacterial endotoxins: | 70 IU/mg max. | ||||||||||||||||
| Residual solvent: |
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Transport Information
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2923200000303 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20 °C |
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Manufacturing Information
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Experience |
Production since 2018 |
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Applications
1. Veterinary Medicine
Used to control and synchronize estrus (heat cycles) in livestock such as cattle, sheep, and pigs.
Facilitates timed artificial insemination and improves reproductive efficiency.
Helps manage reproductive disorders by regulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
2. Human and Animal Reproductive Research
Serves as a tool to study the hypothalamic-pituitary-gonadal axis.
Used in experimental protocols investigating fertility, hormone regulation, and reproductive endocrinology.
3. Potential Clinical Applications
Investigated for therapeutic use in disorders related to hormone imbalance, such as precocious puberty, endometriosis, or hormone-sensitive cancers.
May be used in assisted reproductive technologies (ART) to control ovulation timing.
Benefits
Increased Stability: More resistant to enzymatic breakdown compared to native GnRH, allowing for longer duration of action.
Potent GnRH Agonist: Effectively stimulates the release of LH and FSH, enabling precise control of reproductive cycles.
Improves Breeding Efficiency: Enhances success rates of artificial insemination in livestock.
Versatile Research Tool: Enables detailed study of reproductive hormone dynamics.
Relatively Safe: When used as directed in veterinary applications, it is well-tolerated.
Conclusion
Alarelin (CAS 79561-22-1) is a synthetic GnRH analog with enhanced stability and potency, widely used in veterinary reproductive management to synchronize estrus and improve breeding outcomes. Its application extends to reproductive biology research and holds potential for clinical treatments involving hormonal regulation. Alarelin's ability to precisely modulate gonadotropin release makes it a valuable compound in both agricultural and biomedical contexts.
