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Specifications
| Description: | White to light yellow crystals or crystalline powder, Hygroscopicity |
| Assay: | 900 mg (potency) ~ 970 mg (potency) per mg calculated on the anhydrous basis. The potency of Cefsulodin Sodium is expressed as mass (potency) of Cefsulodin (C22H20N4O8S2: 532.55) |
| Optical Rotation: | +16.5° ~ +20° |
| Absorbance (262 nm): | 250-275 |
| Identification: | 1) Should be a positive reaction 2) Ultraviolet-visible spectrophotometry to attract the maximum at 262 nm 3) HPLC: Conform with Japanese reference standard spectrum 4) Flame reaction of sodium |
| pH: | 3.3-4.8 |
| Solution Clarity and Color: | 8 color liquid max |
| Isonicotinic Acid Amide: | 2.0% max |
| Other Impurities: | 3.0% max |
| Water: | 5.0% max |
| Heavy Metals: | 20 ppm max |
| Bacterial Endotoxin: | Conforms with standard |
Transport Information
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H.S. Code |
2941905400999 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Keep container tightly closed in a dry and well-ventilated place. |
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Package |
Manufacturing Information
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Capacity |
100kg/month |
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Experience |
Production since 2010 |
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Applications
Cefsulodine sodium (CAS 52152-93-9) is a third-generation cephalosporin antibiotic primarily used in pharmaceutical and clinical research. It is utilized for the synthesis and formulation of antibacterial drugs targeting a broad spectrum of Gram-positive and Gram-negative bacteria. In medicinal chemistry, it serves as a reference intermediate or active compound for studying β-lactam antibiotics' structure-activity relationships, stability, and pharmacokinetics. Cefsulodine sodium is also applied in microbiological research for evaluating bacterial susceptibility, resistance mechanisms, and the development of new antibiotic derivatives.
Benefits
The benefits of cefsulodine sodium are derived from its broad-spectrum antibacterial activity, high water solubility, and favorable pharmacokinetic profile. Its β-lactam structure effectively inhibits bacterial cell wall synthesis, leading to rapid bactericidal activity. The sodium salt form enhances solubility and stability, facilitating formulation into oral or parenteral dosage forms. Its efficacy against resistant bacterial strains provides an important tool for managing infections that are difficult to treat with older antibiotics. Additionally, its well-characterized profile allows reliable use in research and drug development for optimizing antibacterial therapies.
Conclusion
Cefsulodine sodium is a potent third-generation cephalosporin with key applications in pharmaceuticals and microbiological research. Its broad-spectrum activity, solubility, and stability make it an effective antibacterial agent and a valuable intermediate for drug development. By supporting both therapeutic use and scientific study, cefsulodine sodium continues to play an important role in advancing antibacterial treatments and antibiotic research.
