Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of cefadroxil monohydrate丨cas 66592-87-8 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Grade | BP2025 |
| Appearance | White or almost white powder |
| Solubility | Slightly soluble in water, very slightly soluble in ethanol (96%) |
| Identification | IR spectrum conforms to reference standard |
| pH | 4.0~6.0 |
| Specific optical rotation | +165°~+178° |
| Impurity A | 1.0% max |
| Any other impurity | 1.0% max |
| Total impurities | 3.0% max |
| Methanol | 3000 ppm max |
| Acetone | 5000 ppm max |
| Water | 4.0%~6.0% |
| Sulfated ash | 0.5% max |
| Assay (anhydrous substance) | 95.0%~102.0% |
| Bulk density (for information only) | 0.59 g/ml |
| Tapped density (for information only) | 0.88 g/ml |
Applications
Cefadroxil monohydrate is widely used in clinical medicine for treating mild to moderate bacterial infections, including skin and soft tissue infections, urinary tract infections, respiratory tract infections, and certain streptococcal infections. In dermatology, it is often prescribed for bacterial skin infections due to its good oral absorption and sustained therapeutic concentration in tissues. In pediatric and outpatient treatments, cefadroxil is valued for its convenient dosing schedule and high patient compliance. In pharmaceutical manufacturing, cefadroxil monohydrate serves as an important raw material and reference standard for antibiotic formulation research and quality control testing. It is also used in microbiology laboratories for susceptibility testing and antimicrobial resistance research.
Benefits
One of the primary benefits of cefadroxil monohydrate is its high oral bioavailability, allowing effective treatment through oral dosage forms without requiring frequent injections. The monohydrate form enhances chemical stability, helping maintain potency during storage and transportation. Cefadroxil works by binding to bacterial penicillin-binding proteins, inhibiting peptidoglycan synthesis and ultimately causing bacterial cell lysis. Compared with some other antibiotics, it generally demonstrates a favorable safety profile and is well tolerated in many patient populations. Its broad-spectrum activity against common pathogens makes it a reliable first-line treatment option for many uncomplicated infections. Additionally, its relatively long half-life allows for less frequent dosing, improving treatment adherence.
Conclusion
Cefadroxil monohydrate is an important first-generation cephalosporin antibiotic with strong clinical and pharmaceutical value. Its good oral absorption, stable formulation characteristics, and broad antibacterial activity make it widely used in infection treatment and pharmaceutical development. As antibiotic resistance continues to be a global healthcare challenge, proper use of cefadroxil and ongoing research into cephalosporin antibiotics remain important for maintaining effective infection control strategies.
