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Specifications
| Appearance: | White to off-white powder |
| Purity: | 85.0% min |
Applications
1. Nucleoside Synthesis Intermediate
Functions as a protected sugar intermediate in the synthesis of modified nucleosides.
Especially relevant in preparing halogenated deoxynucleotides for medicinal or biochemical research.
2. Pharmaceutical & Antiviral Research
Potential precursor for nucleoside analogs with antiviral or anticancer activity.
Can be incorporated into sugar moieties of nucleoside-based prodrugs.
3. Chemical Building Block
Useful in organic synthesis for building chlorinated carbohydrate derivatives or sugar-based scaffolds for complex molecules.
Benefits
Selective Functionalization: The combination of chloro and benzoyl groups provides selective reactivity and stability.
Facilitates Glycosylation Reactions: Good leaving group (chlorine) at the anomeric position supports glycosidic bond formation.
Stable Intermediate: Protected form ensures stability during multi-step syntheses.
Conclusion
1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose (CAS 21740-23-8) is a specialized compound mainly used as an intermediate in the synthesis of nucleoside analogs. Its structure is tailored to protect reactive sites while enabling selective transformation, particularly in medicinal chemistry and bioconjugate synthesis. It is highly valued for its reactive anomeric chloride and electron-withdrawing benzoyl groups, which enhance its synthetic versatility.
