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Specifications
| Appearance | White Crystalline Powder |
| Assay (Titration, Dry basis) | 99% - 101% |
| Water Content | 10.0% max |
| Solubility (25%, 1.0M aqueous) | Colorless, clear |
| Heavy Metals (as Pb) | 5 ppm max |
| Ultraviolet absorbance / 290 nm (20% w/w in 1N NaOH) | 0.1% max |
Applications
POPSO is primarily used as a buffer in biological and biochemical experiments where maintaining stable pH is critical. It is suitable for cell culture, enzyme assays, protein purification, and electrophoresis applications. Its zwitterionic nature ensures minimal interference with biochemical reactions, making it ideal for studies of enzyme kinetics, protein structure, and molecular interactions. In pharmaceutical research, it is employed to formulate stable solutions for drug testing and in vitro assays. Additionally, POPSO is used in analytical chemistry and biotechnology for preparing buffer solutions that require consistent pH under varying temperature conditions and ionic strengths.
Benefits
The key benefits of POPSO include its excellent buffering capacity in the pH range of approximately 6.5–7.9, which is close to physiological conditions. Its zwitterionic structure minimizes interactions with metal ions and biomolecules, reducing the risk of experimental artifacts. POPSO is highly soluble in water, chemically stable, and compatible with a wide range of salts and biological reagents. It maintains consistent pH even under changes in temperature, making it reliable for sensitive biochemical and pharmaceutical applications. Its non-toxic and low-absorbing properties make it suitable for in vitro and in vivo studies.
Conclusion
POPSO is a versatile zwitterionic buffer widely used in biological, biochemical, and pharmaceutical research. Its stable pH range, minimal interference with biomolecules, and chemical stability make it an essential reagent for enzyme assays, protein studies, and drug development. As precise pH control continues to be critical in modern life sciences and pharmaceutical applications, POPSO remains a reliable and valuable buffer solution component.

