Introduction
Sodium Cyanoborohydride (NaBH₃CN), CAS 25895-60-7, is a highly selective and efficient reducing agent widely applied in pharmaceutical synthesis, fine chemicals, and advanced organic reactions. Its ability to perform controlled reductions under mild conditions makes it indispensable for modern chemical manufacturing.
With increasing global demand for high-purity intermediates, sourcing from reliable manufacturers is critical. China has emerged as a major production hub, offering both scale and innovation-where LEAPChem stands out as a trusted, solution-oriented supplier.
Key Chemical Properties
Chemical Formula: NaBH₃CN
Molecular Weight: 62.84 g/mol
Appearance: White to off-white crystalline powder
Purity Range: Typically 95–99.99% depending on grade
Functionality: Selective reduction of imines and aldehydes
Core Applications
1. Reductive Amination
The primary application of Sodium Cyanoborohydride is reductive amination:
Converts aldehydes/ketones into amines efficiently
Minimizes over-reduction
Essential in API synthesis
2. Pharmaceutical Industry
Drug intermediate synthesis
Late-stage functionalization
Modification of bioactive compounds
3. Fine Chemicals & Specialty Materials
Agrochemical intermediates
Electronic chemicals
High-value organic synthesis
Top 10 Sodium Cyanoborohydride Manufacturers in China
China hosts a wide network of manufacturers and suppliers, ranging from specialized fine chemical producers to large-scale exporters. Below is a curated list of key players in this segment:
1. Hangzhou LEAP Chem Co., Ltd. (LEAPChem)
A leading supplier specializing in fine chemicals and pharmaceutical intermediates, offering stable quality, flexible packaging, and global distribution capabilities.
2. Chongqing Soarwin Technology Co., Ltd.
Known for high-purity (up to 99.99%) Sodium Cyanoborohydride and strong supply capacity for industrial and pharmaceutical applications.
3. Nantong Reform Petro-Chemical Co., Ltd.
A diversified chemical manufacturer providing Sodium Cyanoborohydride along with catalysts and specialty chemicals.
4. Hangzhou KieRay Chem Co., Ltd.
Focused on custom synthesis and fine chemicals, with strong R&D collaboration and global export reach.
5. AFINE Chemicals Limited
An established supplier of pharmaceutical intermediates and fine chemicals with international market presence.
6. Shanghai Worldyang Chemical Co., Ltd.
A high-tech enterprise engaged in R&D and large-scale supply of fine chemicals and intermediates for multiple industries.
7. Hebei Chuanghai Biotechnology Co., Ltd.
A cost-competitive supplier with strong OEM/ODM capabilities in chemical intermediates and bulk materials.
8. Henan Fengda Chemical Co., Ltd.
Provides large-scale production and competitive pricing for industrial-grade chemical intermediates.
9. Capot Chemical Co., Ltd.
Specializes in high-purity fine chemicals and building blocks for research and pharmaceutical use.
10. Henan Tianfu Chemical Co., Ltd.
Offers stable supply and multiple packaging options for global customers in pharma and chemical industries.
👉 The Chinese market includes both manufacturers and trading companies, with over a dozen active suppliers offering Sodium Cyanoborohydride products across different purity grades and applications.
Advantages of Sodium Cyanoborohydride
Selective Reactivity
Targets imines without affecting other functional groups.
Mild Reaction Conditions
Operates effectively in weakly acidic environments.
Process Efficiency
Higher yields
Fewer by-products
Easier purification
Why LEAPChem Stands Out
Among numerous suppliers, LEAPChem differentiates itself through:
1. Consistent Quality
Strict quality control ensures ≥95% assay with reliable batch-to-batch consistency.
2. Integrated Supply Chain
From R&D to commercial production, LEAPChem offers end-to-end solutions.
3. Customization Capability
Tailored purity levels
Flexible packaging (gram to ton scale)
Custom synthesis support
4. Global Scientific Supply Network
LEAPChem goes beyond a single product-providing access to:
Pharmaceutical intermediates
Bio-based chemicals
Laboratory reagents
5. Technical Support & Responsiveness
A professional team supports:
Application development
Process optimization
Regulatory documentation
Conclusion
Sodium Cyanoborohydride (CAS 25895-60-7) remains a cornerstone reagent for selective reduction in modern chemistry. As demand continues to grow across pharmaceuticals and specialty chemicals, choosing the right supplier is critical.
While China offers a wide range of manufacturers, LEAPChem combines quality, scalability, and technical expertise, making it a preferred partner for global customers seeking both reliability and innovation.
