Sodium Dodecyl Sulfate丨CAS 151-21-3

Sodium dodecyl sulfate丨151-21-3, with the Chemical Abstracts Service (CAS) number 151-21-3, is an anionic surfactant widely used in scientific research, industrial applications, and consumer products. It consists of a 12-carbon alkyl chain attached to a sulfate group. SDS is known for its ability to reduce surface tension, emulsify oils, and denature proteins, making it a versatile and essential compound in many fields.

1. Laboratory Research:

- Protein Denaturation and Electrophoresis: SDS is a key component of SDS-PAGE (polyacrylamide gel electrophoresis), a technique used to separate proteins based on their molecular weight. It denatures proteins by breaking non-covalent bonds and coats them with a negative charge, allowing for uniform migration in an electric field.

- Cell Lysis: SDS is used to lyse cells and solubilize membrane proteins during protein extraction and purification processes.

2. Industrial and Household Applications:

- Detergents and Cleaning Products: SDS is a common ingredient in household and industrial detergents, shampoos, and soaps due to its excellent foaming and emulsifying properties.

- Emulsification: It is used in the formulation of creams, lotions, and other personal care products to stabilize oil-water mixtures.

3. Pharmaceuticals:

- Sodium dodecyl sulfate丨151-21-3 is used as an excipient in drug formulations to improve the solubility and absorption of active pharmaceutical ingredients (APIs).

4. Biotechnology:

- SDS is used in DNA and RNA extraction protocols to disrupt cell membranes and release nucleic acids.

- It is also employed in the purification of proteins and other biomolecules.

5. Agriculture:

- SDS is used in pesticide formulations to enhance the dispersion and adhesion of active ingredients on plant surfaces.

1. Effective Surfactant:

- SDS is highly effective at reducing surface tension and emulsifying oils, making it a valuable ingredient in cleaning and personal care products.

2. Protein Analysis:

- Its ability to denature proteins and confer a uniform charge makes SDS indispensable in protein electrophoresis and molecular biology research.

3. Versatility:

- SDS is used in a wide range of applications, from laboratory research to industrial manufacturing, due to its unique properties.

4. Cost-Effectiveness:

- Sodium dodecyl sulfate丨151-21-3 is relatively inexpensive and widely available, making it accessible for both research and commercial use.

5. Stability:

- SDS is stable under a wide range of conditions, ensuring its effectiveness in various applications.

While SDS is widely used, it is important to handle it with care due to its potential to cause skin and eye irritation. Proper safety measures, such as wearing gloves and goggles, should be taken when working with SDS. Additionally, its environmental impact should be considered, as it can be toxic to aquatic life at high concentrations.

Sodium dodecyl sulfate丨151-21-3 is a highly versatile and widely used surfactant with applications in laboratory research, industrial processes, and consumer products. Its ability to denature proteins, emulsify oils, and reduce surface tension makes it an essential compound in many fields. Despite its potential hazards, SDS remains a valuable tool due to its effectiveness, affordability, and stability.