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Specifications
| Appearance: | off-white powder |
| Assay (LC): | 98.0% Min |
| Moisture (KF): | 0.5% Max |
Transport Information
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Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2934999099305 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
10MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2021 |
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Stock |
Applications
1. Intermediate in Organic Synthesis
Widely used as a key intermediate in the synthesis of:
Pharmaceuticals (e.g., quinazolinone derivatives, antitumor agents)
Dyes and pigments
Agrochemicals
Reacts readily with amines to form substituted anthranilic acid derivatives and quinazolinones.
2. Synthesis of Heterocyclic Compounds
Important building block for synthesizing benzoxazinones, quinazolines, and benzimidazoles, which are core structures in many drugs and agrochemicals.
3. Pharmaceutical Chemistry
Used to prepare analgesics, anti-inflammatory agents, and antimicrobial compounds.
Enables access to bioactive molecules via ring-opening reactions.
4. Polymer and Material Science
Employed as a monomer or crosslinker in specialty polymers, especially for materials requiring thermal stability and chemical resistance.
Benefits
✅ High Reactivity
The anhydride and lactam functional groups facilitate diverse chemical transformations, allowing for efficient synthesis of complex molecules.
✅ Versatility
Compatible with various nucleophiles (amines, alcohols), enabling broad application in pharmaceutical and material syntheses.
✅ Stable Yet Reactive
Stable under normal conditions but reactive enough for selective ring-opening reactions.
✅ Widely Available
Commercially available in high purity, facilitating ease of use in research and industrial settings.
Conclusion
Isatoic anhydride (CAS 118-48-9) is a crucial intermediate in organic synthesis, especially valuable in the pharmaceutical and agrochemical industries for constructing heterocyclic compounds and bioactive molecules. Its versatility and reactivity enable efficient synthesis of a broad range of important chemical entities, making it indispensable in medicinal chemistry and material science research.
