L-tert-Leucine丨CAS 20859-02-3

L-tert-Leucine丨CAS 20859-02-3
Product Introduction:
CAS No.: 20859-02-3
Product Name: L-tert-Leucine
Grade: Enterprise Standard
Molecular Formula: C6H13NO2
Molecular Weight: 131.17
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Technical Parameters
Description

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Bulk Supply L-tert-Leucine丨CAS 20859-02-3

 

L-tert-Leucine, also known as L-tert-leucine or (S)-2-amino-3,3-dimethylbutanoic acid, is a non-proteinogenic amino acid characterized by its bulky tert-butyl side chain. Its distinctive structure and defined stereochemistry make it a valuable building block in pharmaceutical synthesis, chiral chemistry, and the development of specialized organic compounds. It is particularly relevant to the preparation of chiral intermediates used in pharmaceutical research and manufacturing.

 

Chemical Identifiers

 

InChI InChI=1S/C6H13NO2/c1-6(2,3)4(7)5(8)9/h4H,7H2,1-3H3,(H,8,9)/t4-/m1/s1
InChI Key NPDBDJFLKKQMCM-SCSAIBSYSA-N
Smiles CC(C)(C)[C@@H](C(=O)O)N
EC No. 424-750-7
MDL No. MFCD00064218
PubChem CID 164608

 

 

 

Applications

 

Applications in Pharmaceutical Synthesis

L-tert-Leucine is an important chiral building block for synthesizing pharmaceutical intermediates and biologically active compounds. Its stereochemical configuration and sterically demanding side chain can influence molecular conformation, selectivity, and interactions with biological targets.

Chiral Chemistry and Asymmetric Synthesis

The defined L-configuration of L-tert-leucine makes it useful in research involving stereoselective synthesis. It may be incorporated into chiral auxiliaries, ligands, or other molecular structures designed to influence the formation of stereoisomers during chemical reactions.

Peptide and Organic Synthesis

L-tert-Leucine can serve as a starting material for preparing amino acid derivatives and specialized peptide structures. Its distinctive side chain may be selected when researchers want to modify steric properties, conformational behavior, or the chemical characteristics of a target molecule.

Chemical Research and Intermediate Development

L-tert-Leucine is also useful in organic synthesis and medicinal chemistry research. Its amino and carboxyl groups provide sites for chemical transformation, enabling the preparation of amides, esters, and other derivatives.

 

 

 

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