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Specifications
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Appearance |
Colorless to light yellow transparent liquid |
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Quality Percentage |
22.88% to 23.81% |
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Effective Content |
2.45 to 2.55 M |
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Density |
0.68 g/ml |
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Cl (Chloride) |
0.1% max |
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N-Hexane |
65% to 75% |
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Impurity |
1.0% max |
Transport Information
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Parameter |
Specification |
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UN Number |
3399 |
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Class |
3: 4 |
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Packing Group |
I |
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H.S. Code |
2931900090 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
|
Capacity |
5,000MT/year |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2001 |
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Stock |
Applications of n-Butyllithium丨CAS 109-72-8
1. Strong Base in Organic Synthesis
Widely used as a strong, non-nucleophilic base for deprotonation reactions.
Facilitates metalation reactions where hydrogen atoms are replaced by lithium atoms on aromatic and aliphatic compounds.
Key reagent for preparing organolithium intermediates.
2. Nucleophilic Reagent
Acts as a nucleophile to form new carbon-carbon bonds.
Used in addition reactions to carbonyl compounds, epoxides, and other electrophiles.
3. Synthesis of Pharmaceuticals and Fine Chemicals
Employed to synthesize complex molecules and intermediates in pharmaceutical, agrochemical, and specialty chemical industries.
Enables selective functional group transformations for drug development.
4. Polymerization Initiator
Used as an initiator in anionic polymerization to produce polymers with well-defined structures.
5. Organometallic Synthesis
Utilized to generate other organometallic compounds by transmetalation and metallation techniques.
Benefits
✅ High Reactivity
Extremely strong base and nucleophile, capable of deprotonating weak acids and performing selective lithiation.
✅ Versatility
Applicable to a broad range of synthetic methods and transformations, facilitating complex organic syntheses.
✅ Commercial Availability
Readily available in solution form, making it easy to handle (under inert atmosphere) for laboratory and industrial use.
Summary
n-Butyllithium丨CAS 109-72-8 is a widely used, highly reactive organolithium reagent serving as a strong base and nucleophile in organic synthesis. It plays a crucial role in metalation, carbon–carbon bond formation, polymerization initiation, and organometallic compound preparation. Due to its pyrophoric nature, careful handling and specialized equipment are necessary to ensure safety.
