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Specifications
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Appearance |
Colorless liquid |
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Purity |
99% min |
Transport Information
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2903999090306 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Dry. Containers which are opened must be carefully resealed and kept upright to prevent leakage. |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
10MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2015 |
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Stock |
Applications of 3-Fluoroiodobenzene丨CAS 1121-86-4
1. Pharmaceutical and Agrochemical Synthesis
Widely used as a building block in the synthesis of biologically active compounds.
Serves as a key intermediate in the development of drug candidates, especially in medicinal chemistry involving fluorinated aromatics.
2. Cross-Coupling Reactions
Ideal for Suzuki, Sonogashira, and Heck coupling due to the reactive iodine atom.
Useful in introducing fluorinated aryl groups into complex organic molecules.
3. Materials Science
Applied in the design of organic electronics, OLEDs, and liquid crystal materials, where fluorinated aromatics enhance thermal and electronic properties.
4. Radiolabeling and Tracer Studies
Fluorinated compounds are used in radiopharmaceuticals and PET imaging studies, making this molecule a potential precursor in such applications.
Benefits
✅ Synthetic Versatility
The dual halogen functionality (F and I) enables selective transformations, offering tunable reactivity in multi-step organic synthesis.
✅ Fluorine Effects
The fluorine atom can modulate lipophilicity, metabolic stability, and bioactivity in pharmaceuticals, making it a valuable motif in drug design.
✅ High Reactivity of Iodine
The iodine substituent makes it highly reactive in palladium-catalyzed reactions, allowing efficient C–C and C–N bond formations.
✅ Compact Structure
Small, planar structure allows easy incorporation into aromatic cores of larger molecules.
Summary
3-Fluoroiodobenzene丨CAS 1121-86-4 is a valuable halogenated aromatic intermediate used in pharmaceuticals, agrochemicals, and materials chemistry. Its combination of fluorine and iodine substituents provides synthetic flexibility, particularly for advanced coupling reactions, and contributes to the design of bioactive or electronically functional molecules.
