Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of tetramisole hydrochloride丨cas 5086-74-8 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Appearance: | White to pale cream-coloured crystalline powder |
| Purity: | 98.0% min |
| Identification: | Meets the requirement |
| Appearance of solution: | Meets the requirement |
| UV: | Standard spectrum |
| Loss on drying: | 0.5% max |
| Sulphate ash: | 0.1% max |
| Light absorption: | 0.2 max |
| 2,3-Dihydro-6-phenylimidazo[2.1-b]thiazole HCl: | 0.5 max |
| Odour: | Odourless or almost odourless |
Transport Information
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Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2933199090999 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
10MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2015 |
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Stock |
Applications
1. Veterinary Medicine
Anthelmintic Agent: Widely used to treat gastrointestinal nematode infections in livestock such as cattle, sheep, goats, pigs, and poultry.
Mode of Action: Acts as a cholinergic agonist, causing spastic paralysis in worms by stimulating nicotinic acetylcholine receptors, leading to expulsion from the host.
Broad Spectrum: Effective against both larval and adult stages of many parasitic nematodes, including Haemonchus, Trichostrongylus, Ostertagia, and Ascaris species.
2. Research and Development
Immunomodulatory Studies: Though Levamisole is more commonly used in this context, racemic tetramisole has been studied for stimulating T-cell activity and enhancing immune responses in experimental models.
Cancer Research: Investigated in combination with chemotherapy agents in experimental treatments, particularly in colorectal cancer immunotherapy (again, primarily the L-isomer).
3. Agricultural and Aquaculture Use
Used to deworm fish and aquaculture animals in some regions.
May be incorporated into medicated feed premixes for parasite control in animal husbandry.
Benefits
Effective Anthelmintic: Rapidly active against a wide variety of parasitic worms.
Low Cost: Economical option for mass deworming in livestock industries.
Oral Bioavailability: Can be administered via drench, tablet, or feed additive.
Synergistic Use: Sometimes combined with other dewormers (e.g., benzimidazoles) for broader or enhanced action.
Conclusion
Tetramisole hydrochloride (CAS 5086-74-8) is a potent and cost-effective anthelmintic widely used in veterinary medicine to treat parasitic worm infections. While its human use has declined due to safety concerns, its importance in livestock parasite control, aquaculture, and research remains significant. Proper dosage and adherence to safety guidelines are crucial to ensure its effective and responsible application in animal health management.
