3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine丨CAS 869718-81-0

3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine is a polyethylene glycol (PEG)-based amine widely used in pharmaceutical, biochemical, and materials science applications. Its primary amine functionality makes it a reactive building block for conjugation with carboxylic acids, activated esters, aldehydes, or other electrophiles, enabling the synthesis of PEGylated drugs, peptides, proteins, and functional small molecules. The long PEG chain provides excellent water solubility, reduces aggregation, and enhances biocompatibility, making it ideal for drug delivery systems, bioconjugation, and protein modification. Additionally, it is used in polymer chemistry and nanomaterials as a hydrophilic spacer or linker for surface functionalization, hydrogels, and nanoparticle stabilization.

The benefits of 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine arise from its reactivity, hydrophilicity, and structural flexibility. The primary amine enables selective and efficient conjugation reactions under mild conditions, preserving the functionality of sensitive biomolecules. The long PEG backbone enhances solubility, provides steric flexibility, and minimizes steric hindrance in conjugated systems, improving the performance of drug conjugates and polymeric materials. Its chemical stability and compatibility with both aqueous and organic solvents make it suitable for multi-step syntheses and industrial applications, ensuring reproducible results.