Potassium Vinyltrifluoroborate丨CAS 13682-77-4

Potassium vinyltrifluoroborate (CAS 13682-77-4) is an organoboron compound widely used as a reagent and intermediate in organic synthesis, particularly in cross-coupling reactions. Its primary applications include serving as a vinyl source in Suzuki–Miyaura coupling reactions to construct carbon–carbon double bonds, enabling the synthesis of complex molecules such as pharmaceuticals, agrochemicals, and fine chemicals. It is also utilized in the preparation of functionalized alkenes, heterocycles, and polymer precursors. Its stability, ease of handling, and water solubility make it an attractive alternative to traditional vinylboronic acids or esters in synthetic chemistry.

The benefits of potassium vinyltrifluoroborate stem from its chemical stability, reactivity, and versatility. Unlike many boronic acids, it is air- and moisture-stable, allowing safe storage and handling in the laboratory. Its reactivity in palladium-catalyzed cross-coupling reactions provides high yields and selectivity under mild conditions. Additionally, the trifluoroborate group improves solubility and reduces protodeboronation side reactions, ensuring reproducible and efficient transformations. These properties make it a valuable tool for synthesizing complex molecules with precise control over structure and functionality.