N-(tert-Butyl)benzylamine丨CAS 3378-72-1

N-(tert-Butyl)benzylamine丨CAS 3378-72-1
Product Introduction:
Catalog No.: SS129888
CAS No.: 3378-72-1
Purity: 98%min
Product Name: N-(tert-Butyl)benzylamine
Molecular Formula: C11H17N
Molecular Weight: 163.26
Synonym(s): N-(1,1-Dimethylethyl)benzenemethanamine
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Technical Parameters
Description

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Specifications

 

Appearance: colorless to light yellow liquid
Purity: 98% min
Water: 0.5% max
Impurity: 1.0% max

 

 

 

Applications

 

 

1. Organic Synthesis

Serves as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.

Useful in Schiff base formation and N-alkylation reactions.

2. Pharmaceutical Research

Utilized in developing amine-containing drug scaffolds.

Can be modified to form bioactive compounds with CNS or antimicrobial activity.

3. Ligand/Protecting Group

Acts as a bulky amine ligand or as a protecting group for amines in organic synthesis due to the steric hindrance of the tert-butyl group.

 

Benefits

 

✅ Sterically Hindered Amine

Provides selectivity and control in asymmetric synthesis and catalytic reactions.

✅ Versatile Intermediate

Its benzyl and tert-butyl groups make it an ideal building block for more complex molecules.

✅ Stable and Easily Handled

Liquid form allows for convenient use and storage in labs and manufacturing environments.

✅ Commercial Availability

Readily available and affordable, making it attractive for scale-up processes.

 

Conclusion

 

N-(tert-Butyl)benzylamine (CAS 3378-72-1) is a valuable chemical intermediate used in organic synthesis, medicinal chemistry, and materials science. Its structural features provide both reactivity and selectivity, making it suitable for the synthesis of advanced functional molecules.

 

 

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