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Specifications
| Appearance: | colorless to light yellow liquid |
| Purity: | 98% min |
| Water: | 0.5% max |
| Impurity: | 1.0% max |
Applications
1. Organic Synthesis
Serves as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.
Useful in Schiff base formation and N-alkylation reactions.
2. Pharmaceutical Research
Utilized in developing amine-containing drug scaffolds.
Can be modified to form bioactive compounds with CNS or antimicrobial activity.
3. Ligand/Protecting Group
Acts as a bulky amine ligand or as a protecting group for amines in organic synthesis due to the steric hindrance of the tert-butyl group.
Benefits
✅ Sterically Hindered Amine
Provides selectivity and control in asymmetric synthesis and catalytic reactions.
✅ Versatile Intermediate
Its benzyl and tert-butyl groups make it an ideal building block for more complex molecules.
✅ Stable and Easily Handled
Liquid form allows for convenient use and storage in labs and manufacturing environments.
✅ Commercial Availability
Readily available and affordable, making it attractive for scale-up processes.
Conclusion
N-(tert-Butyl)benzylamine (CAS 3378-72-1) is a valuable chemical intermediate used in organic synthesis, medicinal chemistry, and materials science. Its structural features provide both reactivity and selectivity, making it suitable for the synthesis of advanced functional molecules.

