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Specifications
| Appearance: | White to white low melting point solid |
| Purity: | 98% min |
| Water: | 0.3% max |
Transport Information
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H.S. Code |
2913000090302 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Keep container tightly closed. Store in a cool and shaded area. Keep under inert gas. |
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Condition to Avoid |
Exposure to air. |
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Package |
Manufacturing Information
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Specification |
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Capacity |
10MT/year |
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Experience |
Production since 2018 |
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Stock |
Applications
1. Pharmaceutical Intermediate
Frequently used as a building block in the synthesis of active pharmaceutical ingredients (APIs).
Especially useful in creating fluorinated aromatic compounds, often found in:
Anti-inflammatory drugs
Anticancer agents
Central nervous system (CNS) drugs
2. Agrochemical Synthesis
Used to produce intermediates for herbicides, fungicides, or insecticides.
The halogenated aromatic structure improves bioactivity and target specificity.
3. Organic Synthesis
Functions as a key precursor in forming:
Heterocycles (via condensation or cyclization)
Substituted benzoic acid derivatives
The aldehyde group offers flexibility for reactions such as:
Grignard reactions
Wittig reactions
Reductive aminations
4. Material Science
Can be utilized in functional material research, such as in the synthesis of fluorinated polymers or ligands for metal complexes, although this is less common.
Benefits
| Benefit | Explanation |
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| Versatile Functional Groups | Aldehyde, fluorine, and bromine groups allow multiple synthetic pathways. |
| Enhances Bioactivity | Fluorine and bromine atoms often increase lipophilicity, metabolic stability, and binding affinity in drug and pesticide molecules. |
| Good Intermediate Stability | Allows for easy handling and storage in laboratory and manufacturing conditions. |
| Useful in Fine Chemicals | Ideal for diversifying aromatic rings in medicinal chemistry. |
Conclusion
5-Bromo-2-fluorobenzaldehyde (CAS 93777-26-5) is a valuable synthetic intermediate, especially in pharmaceutical and agrochemical R&D. Its combination of bromine, fluorine, and aldehyde functionalities enables a wide range of chemical transformations, making it highly useful for target-oriented synthesis and complex molecule development.

