Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of 4,6-dichloro-5-pyrimidineacetaldehyde丨cas 16019-33-3 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Appearance: | Yellowish yellow powder |
| Purity (HPLC): | 95% min |
| Identification: | H-NMR, LC-MS |
| Water content: | 1% max |
| Residue on ignition: | 0.5% max |
| Related impurity by HPLC: | Total impurity 5% max |
Applications
1. Pharmaceutical Intermediate
Used as a key building block in the synthesis of pyrimidine-based drugs.
Its reactive aldehyde group allows for further functionalization to generate diverse heterocyclic compounds with potential biological activities such as antiviral or anticancer properties.
2. Agrochemical Synthesis
Acts as an intermediate in the production of pyrimidine-containing herbicides and pesticides.
The chlorinated pyrimidine core enables selective modifications to improve efficacy and target specificity.
3. Organic Synthesis
Used in nucleophilic addition and condensation reactions due to its aldehyde group.
The chlorines on the pyrimidine ring provide sites for nucleophilic aromatic substitution or cross-coupling reactions, allowing complex molecule construction.
Benefits
✔️ Versatile Reactivity
The aldehyde functional group offers a site for diverse chemical transformations.
Chlorine substituents facilitate selective substitution reactions, enhancing synthetic flexibility.
✔️ Important Intermediate
Enables efficient access to complex pyrimidine derivatives widely used in medicinal and agricultural chemistry.
Conclusion
4,6-Dichloro-5-pyrimidineacetaldehyde is a valuable chlorinated pyrimidine intermediate widely employed in pharmaceutical and agrochemical synthesis. Its combination of reactive aldehyde and halogen substituents provides broad chemical utility for constructing bioactive molecules and advanced materials.
