4-Benzloxy-3-methoxybenzaldehyde丨CAS 2426-87-1

4-Benzyloxy-3-methoxybenzaldehyde is a versatile aromatic aldehyde commonly used as an intermediate in pharmaceutical, fragrance, and fine chemical synthesis. Its aldehyde functionality allows for reactions such as condensation, reductive amination, and nucleophilic addition, enabling the preparation of heterocycles, Schiff bases, and other bioactive molecules. The benzyloxy and methoxy substituents provide electron-donating effects that influence reactivity and selectivity, making it suitable for the synthesis of antioxidants, enzyme inhibitors, and CNS-active agents. Additionally, it is used in fragrance chemistry to create aromatic compounds with pleasant odor profiles and in chemical research for structure–activity relationship (SAR) studies and the development of novel functionalized organic molecules.

The benefits of 4-Benzyloxy-3-methoxybenzaldehyde stem from its multifunctional reactivity, chemical stability, and structural versatility. The aldehyde group offers a reactive site for diverse chemical transformations, while the benzyloxy group can serve as a protecting group or be further modified. The methoxy group enhances solubility and electronic properties, facilitating selective reactions. Its high purity and well-defined structure enable reproducible reactions, efficient multi-step synthesis, and high yields in laboratory and industrial applications. The combination of aromatic substitution and aldehyde functionality provides flexibility in synthesizing bioactive compounds, fine chemicals, and fragrance intermediates.