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Specifications of 3-Oxetanemethanol丨CAS 6246-06-6
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Appearance: |
Colorless to yellow liquid |
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HNMR: |
Conforms |
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Purity: |
98% min |
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The Largest Impurity: |
1.0% max |
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Water: |
1% max |
Transport Information of 3-Oxetanemethanol丨CAS 6246-06-6
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Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2932999099117 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. -20 °C. Handle under nitrogen, protect from moisture. Store under nitrogen. |
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Condition to Avoid |
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist. |
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Package |
Manufacturing Information of 3-Oxetanemethanol丨CAS 6246-06-6
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Parameter |
Specification |
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Capacity |
100kg/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2015 |
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Stock |
Overview
3-Oxetanemethanol丨CAS 6246-06-6 is a heterocyclic compound characterized by a strained oxetane ring (a four-membered cyclic ether) with a hydroxymethyl side chain. This structure provides unique reactivity useful in organic synthesis and pharmaceutical chemistry.
Applications
1. Pharmaceutical Intermediate
Used as a building block in the synthesis of bioactive molecules and pharmaceuticals, especially in designing molecules with oxetane rings to enhance drug properties.
Oxetane rings are increasingly employed in medicinal chemistry to improve metabolic stability, aqueous solubility, and bioavailability of drugs.
2. Organic Synthesis
Serves as a versatile intermediate in synthetic routes for the preparation of complex molecules.
The reactive hydroxyl group (-CH2OH) enables further functionalization, while the strained oxetane ring can undergo ring-opening reactions under suitable conditions.
Employed in the synthesis of heterocycles, lactones, and other oxygen-containing frameworks.
3. Material Science
Potential use in polymer chemistry and materials science due to the strained ring system that can influence polymer properties when incorporated.
Benefits
1. Unique Structural Properties
The oxetane ring imparts ring strain, making it a useful reactive site in chemical transformations.
The presence of the hydroxymethyl group allows for versatile chemical modifications.
2. Enhances Drug-like Properties
Incorporation of oxetane rings into drug molecules can improve pharmacokinetics by increasing water solubility and metabolic stability compared to analogous structures.
3. Synthetic Flexibility
Its dual functional groups allow for selective reactions, making it a valuable scaffold in complex molecule synthesis.
Conclusion
3-Oxetanemethanol丨CAS 6246-06-6 is a valuable chemical intermediate notable for its strained oxetane ring and hydroxymethyl group. It is widely used in pharmaceutical and organic synthesis to develop molecules with enhanced stability and bioavailability. Its unique structure provides versatile chemical reactivity, making it an important building block in advanced synthetic and material chemistry.

