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Specifications
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Appearance: |
White to light yellow crystal powder |
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Assay: |
99% min |
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Water: |
0.5% max |
Transport Information
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Parameter |
Specification |
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UN Number |
2671 |
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Class |
6.1 |
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Packing Group |
II |
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H.S. Code |
2932999099304 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
100MT/year |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
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Stock |
2-Aminopyridine丨CAS 504-29-0 is a heterocyclic aromatic amine where an amino group (-NH₂) is attached to the second carbon of a pyridine ring. This compound is a valuable intermediate and building block in various fields, particularly in pharmaceuticals, agrochemicals, and coordination chemistry due to its bifunctional structure (nucleophilic amine and aromatic nitrogen).
Applications
1. Pharmaceutical Industry
Intermediate in drug synthesis: 2-Aminopyridine is commonly used to produce:
Antiviral, anti-inflammatory, and antitumor agents.
Central nervous system stimulants.
Antimalarial and antimicrobial drugs.
Used in the synthesis of famotidine, a widely used histamine H₂ receptor antagonist for treating ulcers and GERD.
4-Aminopyridine, a structural analog, is used for neurological disorders, and research on 2-aminopyridine derivatives explores similar pathways.
2. Agrochemicals
Acts as a precursor or building block in synthesizing:
Herbicides
Fungicides
Insecticides
Used to develop plant growth regulators and pesticide active ingredients.
3. Ligand in Coordination Chemistry
The amine and pyridine nitrogen serve as chelating sites for metals.
Forms stable complexes with transition metals, making it useful in:
Homogeneous catalysis
Materials science
Organometallic synthesis
4. Dye and Pigment Industry
Utilized in the production of azo dyes and other colorants due to its reactive aromatic amine structure.
5. Analytical Chemistry
Acts as a reagent or derivatizing agent for various spectroscopic and chromatographic techniques.
Sometimes used in fluorescent or UV-detectable labeling of molecules.
Benefits and Functional Attributes
Bifunctional molecule: Reactivity through both the amino group and the pyridine ring.
High nucleophilicity: Amino group enables substitution, condensation, and acylation reactions.
Stable aromatic system: Provides structural integrity in drug scaffolds and metal complexes.
Summary
2-Aminopyridine丨CAS 504-29-0 is a versatile chemical used as a pharmaceutical intermediate, agrochemical precursor, and ligand in coordination chemistry. Its bifunctional nature-combining an electron-rich amino group and a heteroaromatic pyridine ring-makes it a critical building block for developing bioactive molecules and functional materials.
