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Specifications
|
Appearance |
Colorless to light yellow liquid |
|
Purity |
98% min |
|
Water (KF) |
0.5% max |
Applications
1. Intermediate in Organic Synthesis
● 2,5-Dibromotoluene丨CAS 615-59-8 is primarily used as a synthetic intermediate in the manufacture of pharmaceuticals, agrochemicals, and fine chemicals.
● The bromine atoms serve as reactive sites for cross-coupling reactions (e.g., Suzuki, Heck, Stille), enabling the formation of more complex molecules.
2. Building Block in Material Science
● Serves as a precursor for the development of advanced materials, including liquid crystals, OLEDs, and conducting polymers.
● The presence of dual bromines allows for selective substitution and functionalization in polymer chemistry.
3. Synthesis of Functionalized Aromatics
● Used in the preparation of diaryl compounds, heterocycles, and aromatic amines through bromine substitution or metal-catalyzed reactions.
● Its methyl group can be further oxidized or modified, adding versatility to its synthetic utility.
Benefits
1. Versatile Reactivity
● Dual bromine substituents offer multiple functionalization points, making it a useful starting material for multi-step organic syntheses.
● Compatible with metal-catalyzed cross-coupling, enabling efficient formation of C–C and C–N bonds.
2. High Selectivity in Derivative Formation
● Substitution at 2,5-positions leads to symmetrical products, which is advantageous in synthesizing materials with uniform electronic properties (e.g., for optoelectronic applications).
3. Stable and Easy to Handle
● Chemically stable under normal storage conditions, and its solid form allows for convenient handling, weighing, and storage in laboratories and manufacturing environments.
Conclusion
2,5-Dibromotoluene丨CAS 615-59-8 is a valuable chemical intermediate with broad applicability in organic synthesis, materials science, and pharmaceutical R&D. Its reactive bromine atoms and modifiable methyl group allow for diverse chemical transformations, especially in cross-coupling reactions. While it is generally stable and easy to handle, proper safety measures should be followed due to its irritant properties.
