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Specifications of Sodium Phosphate, Dibasic, Heptahydrate丨CAS 7782-85-6
|
Item |
Specification |
|
Grade |
USP2024 |
|
Appearance |
Colorless or white, granular or caked salt. Its solutions are alkaline to phenolphthalein TS, a 0.1M solution having a pH of about 9. Effloresces in warm, dry air. |
|
Assay (calculated on the dried basis) |
98% to 100.5% |
|
Solubility |
Freely soluble in water, very slightly soluble in alcohol |
|
Identification A |
Chemical reaction - Sodium |
|
Identification B |
Chemical reaction - Phosphate |
|
Loss on Drying |
43% to 50% |
|
Insoluble Substances |
0.4% max |
|
Chloride |
0.06% max |
|
Sulfate |
0.2% max |
|
Arsenic |
16 ppm max |
|
TAMC |
1000 cfu/g max |
|
TYMC |
100 cfu/g max |
|
E. coli |
Negative |
|
Bacterial Endotoxin |
2.5 EU/g max |
Overview
Sodium Phosphate, Dibasic, Heptahydrate丨CAS 7782-85-6 is an inorganic salt commonly used in buffering solutions, industrial processes, food formulations, and water treatment. As a hydrated form of disodium phosphate, it plays a key role in pH regulation, water softening, and chemical preparation, owing to its alkalinity and excellent solubility.
Applications of Sodium Phosphate, Dibasic, Heptahydrate丨CAS 7782-85-6
1. Laboratory and Biotechnology
● Buffering Agent:
oWidely used in biological buffers, including PBS (phosphate-buffered saline).
oHelps maintain physiological pH in biochemical reactions, especially enzyme studies and cell culture.
● Reagent in Analytical Chemistry:
oUsed in the preparation of reagents and solutions for spectroscopy, titrations, and analytical assays.
2. Pharmaceutical and Medical Uses
● Laxative and Osmotic Agent:
oIncorporated in oral solutions or enemas for bowel cleansing prior to medical procedures (e.g., colonoscopy).
oDraws water into the colon, facilitating evacuation.
● Pharmaceutical Excipient:
oServes as a stabilizer or pH buffer in injectable drugs, tablets, and suspensions.
3. Food and Beverage Industry
● Emulsifier and Stabilizer:
oUsed in processed cheese, dairy products, and meats to regulate texture, moisture, and pH.
● Food-Grade Buffer:
oSodium Phosphate, Dibasic, Heptahydrate丨CAS 7782-85-6 helps prevent spoilage by adjusting acidity and preserving product consistency.
4. Water Treatment
● Water Softening:
oBinds calcium and magnesium ions to reduce hardness and prevent scale formation.
● Corrosion Inhibitor:
oHelps protect metal surfaces in boiler and cooling water systems.
5. Detergents and Cleaners
● Acts as a builder in detergents, enhancing cleaning efficiency by softening water.
● Used in industrial degreasers and cleaning formulations for metals and glass.
6. Agriculture and Fertilizers
● Nutrient Additive:
oOccasionally used as a phosphorus source in fertilizers for soil enrichment.
Benefits of Sodium Phosphate, Dibasic, Heptahydrate丨CAS 7782-85-6
√ Excellent Buffering Capacity
● Maintains stable pH in biological, chemical, and food systems.
√ Highly Soluble and Versatile
● Its hydrated form ensures easy dissolution, making it ideal for aqueous solutions and suspensions.
√ Food and Pharma Safe
● Generally recognized as safe (GRAS) when used within prescribed limits.
√ Non-Toxic and Biocompatible
● Suitable for use in medical and pharmaceutical applications with minimal side effects when properly dosed.
√ Cost-Effective and Readily Available
● Widely manufactured and affordable, with multiple grades (analytical, food, pharmaceutical).
Conclusion
Sodium Phosphate, Dibasic, Heptahydrate丨CAS 7782-85-6 is a versatile inorganic compound with wide-ranging uses in buffer solutions, medical preparations, food processing, and industrial systems. Its effectiveness in pH regulation, water treatment, and chemical formulation makes it a critical component across many sectors, valued for its safety, solubility, and stability.

