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Specifications of Microcrystalline Cellulose | CAS 9004-34-6
|
Property |
Specification |
|
Grade |
PH 101/USP 40 |
|
Appearance |
White or similar white, fine or granular powder |
|
Assay |
97% to 102% |
|
Polymerization |
350 max |
|
Granulometry |
Remains 60 mesh <1%, remains 200 mesh >30% |
|
Conductivity |
75 µS/cm max |
|
pH Value |
5.0 to 7.5 |
|
Loss on Drying |
7.0% max |
|
Residue on Ignition |
0.1% max |
|
Water Soluble Substance |
0.25% max |
|
Ether-Soluble Substances |
0.05% max |
|
Heavy Metal |
10 ppm max |
|
Total Aerobic Microbial Count (TAMC) |
1000 cfu/g max |
|
Total Yeast and Mold Count (TYMC) |
100 cfu/g max |
Transport Information of Microcrystalline Cellulose | CAS 9004-34-6
|
Parameter |
Specification |
|
UN Number |
|
|
Class |
|
|
Packing Group |
|
|
H.S. Code |
3912900000101 |
|
Stability & Reactivity |
Stable |
|
Storage |
Store in a closed, dry, ventilated place |
|
Condition to Avoid |
Open flames, hot surfaces and sources of ignition |
|
Package |
20kg/bag |
Manufacturing Information of Microcrystalline Cellulose | CAS 9004-34-6
|
Parameter |
Specification |
|
Capacity |
200MT/month, 2865MT/year |
|
Frequency |
|
|
Main Export Countries |
|
|
Capacity/Batch |
|
|
Experience |
Production since 2005 |
|
Facilities |
Introduction of Microcrystalline Cellulose | CAS 9004-34-6
Microcrystalline Cellulose (MCC) | CAS 9004-34-6 is a purified, partially depolymerized cellulose derived from natural plant fibers. Widely utilized across the pharmaceutical, food, and cosmetic industries, MCC is renowned for its versatility as a functional excipient. With its unique properties, MCC enhances product performance and quality in a variety of applications.
Applications of Microcrystalline Cellulose | CAS 9004-34-6
1. Pharmaceutical Industry:
- Tablet and Capsule Formulations: Microcrystalline cellulose is commonly used as a binder and filler in tablet and capsule manufacturing. Its excellent compressibility allows for strong, durable tablets produced via direct compression or wet granulation techniques.
- Controlled-Release Systems: Microcrystalline Cellulose can be used in controlled-release formulations, ensuring the consistent and gradual release of active ingredients.
2. Food Industry:
- Food Additive: Microcrystalline cellulose serves as an anti-caking agent, stabilizer, and texturizer in food products, improving texture, shelf life, and consistency.
- Calorie Reduction: As a fat substitute, MCC is included in low-calorie foods to enhance mouthfeel without adding significant calories.
3. Cosmetics and Personal Care:
- Thickener and Stabilizer: In creams, lotions, and other cosmetic formulations, MCC acts as a stabilizer and thickening agent, providing desirable texture and consistency.
- Exfoliating Agent: Its granular form is sometimes incorporated into skincare products for gentle exfoliation.
Benefits of Microcrystalline Cellulose | CAS 9004-34-6
1. Exceptional Binding Properties:
- Microcrystalline Cellulose provides robust binding in tablet formulations, ensuring the production of high-quality tablets that maintain their structural integrity during handling and storage.
2. Versatility in Formulations:
- It is compatible with a wide range of active pharmaceutical ingredients (APIs) and excipients, allowing formulators to create diverse product types across industries.
3. Enhanced Stability:
- Microcrystalline cellulose is chemically stable, non-reactive, and resistant to moisture, making it an excellent choice for formulations requiring long-term stability.
4. Improved Product Performance:
- In addition to its role as a binder and filler, MCC improves the disintegration and dissolution rates of tablets, contributing to the bioavailability of active ingredients.
5. Safe and Non-Toxic:
- MCC is recognized as safe (GRAS) by regulatory authorities, ensuring consumer confidence and compliance with global standards.
Precautions and Considerations of Using Microcrystalline Cellulose | CAS 9004-34-6
1. Moisture Sensitivity:
- Although MCC is stable, its performance can be impacted by excessive moisture. Proper storage in dry, controlled environments is essential.
2. Particle Size Variability:
- The functionality of Microcrystalline Cellulose can vary depending on its particle size and grade. Selecting the appropriate type for specific applications is crucial to achieving desired results.
3. Compatibility Testing:
- As with any excipient, compatibility testing with active ingredients is necessary to avoid unexpected interactions and ensure product stability.
Conclusion:
Microcrystalline Cellulose | CAS 9004-34-6 is a cornerstone excipient in pharmaceutical, food, and cosmetic industries. Its unmatched binding, stabilizing, and texturizing properties make it an indispensable choice for manufacturers seeking consistent, high-quality results. By enabling precise formulation control and enhancing product stability, MCC ensures the development of safe, effective, and consumer-friendly products across a wide array of applications.

