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Specifications
| Appearance | Off white to light yellow crystalline powder |
| Assay(HPLC) | 99% min |
| Melting point | 213–216 °C |
| Water | 0.3% max |
Transport Information
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H.S. Code |
2917399090306 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
Oxidizing agents |
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Package |
Manufacturing Information
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Capacity |
600MT/year |
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Main Export Countries |
EU, US, Russia |
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Experience |
Production since 2019 |
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Stock |
Applications
1. Intermediate in Organic Synthesis
Pharmaceutical Intermediates: 3-Nitrophthalic acid is used as a building block for synthesizing complex organic compounds, including intermediates for pharmaceutical active ingredients.
Dye Intermediates: It serves as a precursor in the synthesis of azo dyes, where the nitro group can be reduced to an amine for coupling reactions.
Agrochemical Intermediates: It is used in the synthesis of herbicides, fungicides, and insecticides.
2. Polymer and Resin Synthesis
Used in the preparation of specialty polyimides, polyesters, or copolymers, particularly when functionalized aromatic dicarboxylic acids are needed for high-performance materials with thermal and mechanical stability.
Crosslinking Agent: Its carboxyl groups can form ester or amide linkages in polymers, enhancing crosslinking density and improving physical properties.
3. Ligand and Coordination Chemistry
The compound can be used to synthesize chelating ligands due to the positioning of carboxylic acid groups, which can coordinate to metals in catalyst or MOF (metal–organic framework) design.
In coordination polymers and supramolecular chemistry, it acts as a rigid linker for constructing organized frameworks.
4. Reduction Product for Amino Derivatives
Upon reduction of the nitro group (e.g., catalytic hydrogenation), it yields 3-aminophthalic acid, an important intermediate in dyes and fluorescent compounds.
Benefits
Versatile Functional Groups: Contains both electron-withdrawing (NO₂) and acidic (COOH) groups, enabling a wide array of chemical modifications.
Thermal Stability: Its aromatic structure makes it suitable for high-temperature polymer applications.
Enhanced Solubility in Polar Solvents: Due to its polar groups, it dissolves well in solvents like DMSO, DMF, or aqueous alkaline solutions.
Useful Precursor for Tailored Molecules: Allows design of molecules with specific electronic, optical, or coordination properties.
Eco-Friendly Alternative in Dyes: Nitro-functionalized precursors reduce the need for toxic heavy metal dyes when converted to azo dyes.
Conclusion
3-Nitrophthalic acid (CAS 603-11-2) is a valuable specialty chemical, widely used as a synthetic intermediate in pharmaceuticals, dyes, and advanced materials. Its dual carboxylic acid functionality and nitro group offer significant chemical flexibility, allowing it to serve as a key platform compound in research and industrial chemistry. Its applications in polymers, coordination compounds, and fine chemicals make it an indispensable compound in modern synthetic and materials chemistry.
