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L-Citrulline DL-Malate丨CAS 54940-97-5 Manufacturer
L-Citrulline DL-Malate is a compound combining L-citrulline, a non-proteinogenic amino acid involved in the urea cycle, with malic acid, an organic acid associated with cellular energy metabolism. It is widely used in sports nutrition research, dietary supplement development, biochemical studies, and specialized nutritional formulations. Its combination of amino acid and organic acid components makes it relevant to research into nitrogen metabolism, exercise physiology, and energy-related biochemical pathways.
Chemical Identifiers
| InChI | InChI=1S/C6H13N3O3.C4H6O5/c7-4(5(10)11)2-1-3-9-6(8)12;5-2(4(8)9)1-3(6)7/h4H,1-3,7H2,(H,10,11)(H3,8,9,12);2,5H,1H2,(H,6,7)(H,8,9)/t4-;/m0./s1 |
| InChI Key | DROVUXYZTXCEBX-WCCKRBBISA-N |
| Smiles | C(C[C@@H](C(=O)O)N)CNC(=O)N.C(C(C(=O)O)O)C(=O)O |
| EC No. | 927-830-4 |
| MDL No. | |
| PubChem CID | 162762 |
Applications
Applications in Nutritional Supplements
L-Citrulline DL-Malate is commonly used as an ingredient in sports nutrition formulations, particularly pre-workout products. L-citrulline participates in the body's arginine-related metabolic pathways and contributes to nitric oxide production, which is involved in vascular function. Malate is associated with cellular energy metabolism. The ingredient is therefore of interest in research and formulation development related to exercise performance and physical endurance, although outcomes depend on the formulation, dose, and supporting evidence.
Dietary Supplements and Nutritional Formulations
L-Citrulline DL-Malate is used in selected dietary supplements designed for active individuals and sports nutrition consumers. It may be incorporated into powders, drink mixes, and other formulations where amino acid and organic acid ingredients are desired. Product developers should evaluate ingredient identity, composition, solubility, sensory characteristics, and stability to ensure compatibility with the finished formulation.
Pharmaceutical and Formulation Development
Biochemical and Metabolic Research
L-Citrulline is involved in the urea cycle, a metabolic pathway that helps convert excess nitrogen into urea for excretion. It is also connected to arginine metabolism and nitric oxide biosynthesis. L-Citrulline DL-Malate may be used in suitable laboratory studies investigating amino acid metabolism, nitrogen balance, and related physiological processes. Research involving the combined ingredient should account for the properties and proportions of both citrulline and malate.
