Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of Furan-3-boronic acid丨CAS 55552-70-0 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Ordering Online Furan-3-boronic acid丨CAS 55552-70-0
Furan-3-boronic acid, CAS 55552-70-0, is a heteroaromatic boronic acid featuring a boronic acid group attached to the 3-position of a furan ring. Its structure combines the distinctive electronic properties of the oxygen-containing furan heterocycle with the synthetic versatility of an organoboron functional group. As a useful building block in modern organic synthesis, it is particularly valuable for carbon–carbon bond formation through palladium-catalyzed Suzuki–Miyaura cross-coupling reactions. The resulting furan-containing compounds are important structural motifs in pharmaceutical research, agrochemical development, and functional organic materials.
Chemical Identifiers
| InChI | 1S/C4H5BO3/c6-5(7)4-1-2-8-3-4/h1-3,6-7H |
| InChI Key |
CYEFKCRAAGLNHW-UHFFFAOYSA-N |
| Smiles | OB(C1=COC=C1)O |
| EC No. | 672-302-6 |
| MDL No. | MFCD01319007 |
| PubChem CID | 2734358 |
Applications
Applications in Heterocyclic Compound Synthesis
The furan ring is an important five-membered oxygen-containing heterocycle found in many synthetic and naturally occurring compounds. Furan-3-boronic acid provides a convenient route to 3-substituted furan derivatives through carbon–carbon coupling reactions. By selecting different coupling partners, chemists can prepare a diverse range of substituted furans and more complex heterocyclic structures. These products can serve as intermediates for further functionalization, enabling the construction of molecular libraries and the exploration of new heteroaromatic chemical structures.
Applications in Agrochemical Research
Furan-containing structures are also relevant to the design and synthesis of specialty agrochemicals and crop-protection research compounds. Furan-3-boronic acid can be used to introduce a furan moiety into selected molecular frameworks, helping researchers explore structural variations and develop new heteroaromatic intermediates. Its cross-coupling reactivity supports the preparation of compounds with different substituent patterns for synthetic investigation and structure–activity relationship studies.
Applications in Pharmaceutical Intermediate Synthesis
Furan-3-boronic acid is a useful intermediate for preparing heteroaryl-containing compounds in pharmaceutical research. Through Suzuki–Miyaura cross-coupling with suitable aryl or heteroaryl halides, it enables the introduction of a furan ring into more complex molecular structures. Furan-containing scaffolds are frequently explored in medicinal chemistry because their heteroaromatic character can influence molecular polarity, electronic distribution, and interactions with biological targets. This makes the compound relevant to the development of pharmaceutical intermediates and the synthesis of candidate molecules for drug discovery.
Applications in Functional Organic Materials
The furan heterocycle offers useful electronic and structural characteristics for the development of functional organic molecules. Furan-3-boronic acid can serve as a building block for preparing conjugated heteroaromatic compounds through coupling with suitable aromatic partners. Such products may be investigated in organic electronic materials, functional polymers, and other advanced material systems. The ability to introduce different aromatic groups at the 3-position provides flexibility when adjusting molecular structure and electronic properties.
