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Specifications
| Grade: | EP 11.0 |
| Appearance: | White or almost white powder |
| IR identification: | Complies with reference spectrum |
| Total impurities: | 3% max |
| Impurity A (Fenbendazole): | 1% max |
| Impurity B (Peroxide): | 2% max |
| Impurity C: | 1% max |
| Impurity D: | 1% max |
| Other unspecified impurities: | 0.1% max |
| Loss on drying: | 0.5% max |
| Sulfated ash: | 0.2% max |
| Assay (dried substance): | 97.5% - 100.5% |
Applications
Oxfendazole is a broad-spectrum benzimidazole anthelmintic widely used in veterinary medicine to control gastrointestinal and respiratory parasitic infections in livestock, including cattle, sheep, goats, pigs, and horses. It is effective against nematodes, cestodes, and certain lungworms, making it a critical component in herd health management and parasite control programs. Oxfendazole can be administered orally via drench, feed, or bolus, allowing flexible dosing strategies for both individual animals and large herds. Beyond livestock, it is also used in companion animal health for specific parasitic infections. Its mechanism of action, which disrupts microtubule formation in parasites, ensures rapid and effective eradication of worms while reducing the likelihood of resistance when used appropriately. Additionally, Oxfendazole is utilized in research to study parasitic biology and drug efficacy, supporting the development of new antiparasitic treatments.
Benefits
The benefits of Oxfendazole stem from its broad-spectrum activity, high efficacy, and safety profile. It provides potent and reliable control of multiple parasitic species, which helps improve animal health, growth performance, and productivity. Its relatively long half-life ensures sustained antiparasitic activity, reducing the frequency of dosing and enhancing convenience for livestock management. Oxfendazole is well-tolerated in animals at therapeutic doses, exhibiting minimal toxicity while effectively targeting parasites. Its use reduces parasitic load, decreases economic losses associated with infection, and helps prevent secondary complications such as anemia, weight loss, and reduced milk or meat production. Furthermore, it can be incorporated into integrated parasite management programs alongside other preventive measures to maintain long-term herd health and sustainability.
Conclusion
Oxfendazole (CAS 53716-50-0) is a highly effective anthelmintic for the control of gastrointestinal and respiratory parasites in livestock and certain companion animals. Its broad-spectrum efficacy, safety, and prolonged action make it a cornerstone in veterinary parasite management. By improving animal health, productivity, and welfare, Oxfendazole contributes to sustainable livestock production and supports ongoing research in parasitology and drug development.

