Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of iopromide丨cas 73334-07-3 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Grade: | EP10.0 |
| Characteristics: | White or yellowish crystalline powder |
| Assay (on anhydrous): | 97.0–102.0% |
| Identification: | Complies |
| Solution: | The solution is clear and not more intensely coloured than reference solutions BY6, B6, and Y6 |
| Conductivity: | 50 µS/cm-1 max |
| Water: | 1.5% max |
| Sulphated ash: | 0.1% max |
| Related Substances | |
| Impurity A and related primary aromatic amines: | 0.01% max |
| Impurity B: | 1.5% max |
| Impurity C: | 0.5% max |
| Impurity D: | 1.0% max |
| Impurity E: | 0.5% max |
| Isomer Composition | |
| Z1 + E1 (of total isomers): | 40% – 51% |
| Z2 + E2 (of total isomers): | 49% – 60% |
| Bacterial Endotoxins: | 1.0 EU/mg max |
| Free iodide: | The upper layer remains colorless |
| Inorganic iodide: | 2 ppm max |
Applications
1.1 Diagnostic Imaging (Primary Use)
Iopromide is a nonionic, water-soluble radiographic contrast agent widely used in X-ray and computed tomography (CT) imaging. It enhances the visibility of internal organs and vascular structures by absorbing X-rays, improving diagnostic accuracy.
Major applications include:
CT scans of the chest, abdomen, pelvis, and brain
Angiography (coronary, cerebral, pulmonary, renal, and peripheral vessels)
Urography
Venography and arteriography
Intravenous pyelography
Myelography (in some formulations)
1.2 Interventional Radiology and Cardiology
Used during minimally invasive image-guided procedures, such as:
Cardiac catheterization
Stent or balloon angioplasty
Thrombolytic therapies
Embolization procedures
1.3 Pediatric Imaging
Due to its favorable safety profile, iopromide is also used in:
Pediatric CT and urography
Congenital heart defect diagnostics
Renal function assessment
1.4 Off-label and Research Use
In addition to human diagnostics, iopromide is occasionally utilized in:
Veterinary imaging
Experimental studies on vascular permeability and drug delivery
Benefits
2.1 Nonionic and Low Toxicity
Iopromide is nonionic and monomeric, resulting in:
Lower osmolality compared to ionic contrast media
Reduced risk of adverse reactions, such as allergic responses and nephrotoxicity
2.2 High Water Solubility and Stability
Easily injectable in various concentrations
Compatible with physiological conditions
Provides consistent imaging quality
2.3 Excellent Radiopacity
The three iodine atoms per molecule provide high contrast during radiographic imaging, ensuring:
Sharp anatomical delineation
Clear visualization of soft tissues, blood vessels, and organ systems
2.4 Rapid Renal Elimination
Cleared quickly through the kidneys
Minimal residual retention in tissues
Lower risk of long-term accumulation, especially in healthy renal function
2.5 Favorable Safety Profile
Low incidence of adverse cardiovascular, renal, or hypersensitivity events
Suitable for outpatient diagnostic procedures
Well-tolerated in both adults and children
Conclusion
Iopromide (CAS 73334-07-3) is a widely trusted, nonionic iodinated contrast agent that has become a cornerstone in modern diagnostic imaging. Its excellent safety profile, high contrast efficiency, and compatibility with a wide range of imaging techniques make it ideal for enhancing visibility during CT scans, angiography, and urography. Its nonionic nature significantly reduces the incidence of adverse reactions, offering safer and more comfortable imaging for patients across various age groups and clinical conditions. As imaging technology advances, agents like iopromide continue to play a vital role in early detection, accurate diagnosis, and precise interventional procedures in both human and veterinary medicine.
