Methoxypolyethylene Glycols丨CAS 9004-74-4

Methoxypolyethylene Glycols丨CAS 9004-74-4
Product Introduction:
Catalog No.: SS111839
CAS No.: 9004-74-4
M.W.: 315~384
Product Name: Methoxypolyethylene glycols
Molecular Formula: CH3O.(C2H4O)n.H
Synonym(s): Poly(ethylene glycol) monomethyl ether; MPEG
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Technical Parameters
Description

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Specifications of Methoxypolyethylene glycols丨CAS 9004-74-4

 

Appearance:

Colorless to light yellow transparent liquid

Hydroxyl value:

146~178 mgKOH/g

M.W.:

315~384

Water Content:

1.0% max

pH (1%):

5.0~7.0

 

Transport Information of Methoxypolyethylene glycols丨CAS 9004-74-4

 

Parameter

Specification

UN Number

 

Class

 

Packing Group

 

H.S. Code

2909499090999

Stability & Reactivity

The product is chemically stable under standard ambient conditions.

Storage

Suggested storage temperature -20 ° C

Condition to Avoid

 

Package

 

 

 

 

Overview

Methoxypolyethylene glycols丨CAS 9004-74-4 are a family of nonionic, water-soluble polymers with diverse applications in pharmaceuticals, personal care, coatings, and industrial processes. They vary in molecular weight (from a few hundred to several thousand Daltons), affecting their physical properties and functionality.


 

Applications

1. Pharmaceuticals and Biomedicine

Drug Delivery (PEGylation):
Methoxypolyethylene glycols丨CAS 9004-74-4 are used to modify proteins, peptides, and small-molecule drugs via PEGylation, which:

Enhances drug solubility and bioavailability

Reduces immunogenicity and proteolytic degradation

Prolongs circulation time in the body

Excipient in Formulations:
MPEGs are used as solubilizers, binders, or stabilizers in tablets, creams, and injectable formulations.


2. Cosmetics and Personal Care

Humectants and Emollients:
MPEGs help retain moisture and improve skin feel in lotions, creams, shampoos, and conditioners.

Solubilizing Agents:
Improve the dispersion of active ingredients in aqueous or alcohol-based formulations.

Surfactant and Thickener:
Contribute to foam formation and texture in cleansing products.


3. Industrial Applications

Coatings and Adhesives:
MPEG-modified resins offer improved flow, water solubility, and compatibility with other components, used in:

Waterborne paints

Inks

Pressure-sensitive adhesives

Polyurethane Production:
MPEGs are used as polyols in the synthesis of polyurethane foams and elastomers, where they help tune flexibility and hydrophilicity.


4. Textile, Paper, and Leather Processing

Serve as lubricants, antistatic agents, or softeners, improving material handling, surface feel, and finish quality.


5. Chemical Synthesis and Surfactant Manufacture

Macromolecular Building Blocks:
MPEGs are often used in the production of nonionic surfactants, emulsifiers, and dispersants in various formulations.


 

Benefits

1. Water Solubility and Biocompatibility

MPEGs are highly water-soluble and exhibit low toxicity, making them safe and effective for biomedical and cosmetic use.

2. Tailorable Molecular Weight

Available in a range of molecular weights, enabling customization of viscosity, solubility, and reactivity.

3. Nonionic and Chemically Stable

MPEGs are nonionic, making them compatible with ionic and nonionic systems, and stable across a wide pH range.

4. Enhanced Product Performance

Improve spreadability, moisture retention, and shelf life of consumer and industrial products.


 

Conclusion

Methoxypolyethylene glycols丨CAS 9004-74-4 are versatile, water-soluble polymers with a wide range of pharmaceutical, cosmetic, industrial, and chemical applications. Known for their biocompatibility, tunable properties, and chemical stability, MPEGs are essential ingredients in drug delivery systems, personal care products, coatings, and polyurethane formulations. Their continued utility in emerging biotechnologies and sustainable materials further highlights their importance in modern science and industry.

 

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