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Specifications of Methoxypolyethylene glycols丨CAS 9004-74-4
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Appearance: |
Colorless to light yellow transparent liquid |
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Hydroxyl value: |
146~178 mgKOH/g |
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M.W.: |
315~384 |
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Water Content: |
1.0% max |
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pH (1%): |
5.0~7.0 |
Transport Information of Methoxypolyethylene glycols丨CAS 9004-74-4
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2909499090999 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Suggested storage temperature -20 ° C |
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Condition to Avoid |
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Package |
Overview
Methoxypolyethylene glycols丨CAS 9004-74-4 are a family of nonionic, water-soluble polymers with diverse applications in pharmaceuticals, personal care, coatings, and industrial processes. They vary in molecular weight (from a few hundred to several thousand Daltons), affecting their physical properties and functionality.
Applications
1. Pharmaceuticals and Biomedicine
Drug Delivery (PEGylation):
Methoxypolyethylene glycols丨CAS 9004-74-4 are used to modify proteins, peptides, and small-molecule drugs via PEGylation, which:
Enhances drug solubility and bioavailability
Reduces immunogenicity and proteolytic degradation
Prolongs circulation time in the body
Excipient in Formulations:
MPEGs are used as solubilizers, binders, or stabilizers in tablets, creams, and injectable formulations.
2. Cosmetics and Personal Care
Humectants and Emollients:
MPEGs help retain moisture and improve skin feel in lotions, creams, shampoos, and conditioners.
Solubilizing Agents:
Improve the dispersion of active ingredients in aqueous or alcohol-based formulations.
Surfactant and Thickener:
Contribute to foam formation and texture in cleansing products.
3. Industrial Applications
Coatings and Adhesives:
MPEG-modified resins offer improved flow, water solubility, and compatibility with other components, used in:
Waterborne paints
Inks
Pressure-sensitive adhesives
Polyurethane Production:
MPEGs are used as polyols in the synthesis of polyurethane foams and elastomers, where they help tune flexibility and hydrophilicity.
4. Textile, Paper, and Leather Processing
Serve as lubricants, antistatic agents, or softeners, improving material handling, surface feel, and finish quality.
5. Chemical Synthesis and Surfactant Manufacture
Macromolecular Building Blocks:
MPEGs are often used in the production of nonionic surfactants, emulsifiers, and dispersants in various formulations.
Benefits
1. Water Solubility and Biocompatibility
MPEGs are highly water-soluble and exhibit low toxicity, making them safe and effective for biomedical and cosmetic use.
2. Tailorable Molecular Weight
Available in a range of molecular weights, enabling customization of viscosity, solubility, and reactivity.
3. Nonionic and Chemically Stable
MPEGs are nonionic, making them compatible with ionic and nonionic systems, and stable across a wide pH range.
4. Enhanced Product Performance
Improve spreadability, moisture retention, and shelf life of consumer and industrial products.
Conclusion
Methoxypolyethylene glycols丨CAS 9004-74-4 are versatile, water-soluble polymers with a wide range of pharmaceutical, cosmetic, industrial, and chemical applications. Known for their biocompatibility, tunable properties, and chemical stability, MPEGs are essential ingredients in drug delivery systems, personal care products, coatings, and polyurethane formulations. Their continued utility in emerging biotechnologies and sustainable materials further highlights their importance in modern science and industry.

