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Specifications of Ethylboronic acid丨CAS 4433-63-0
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Appearance |
Off white crystal |
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Purity (GC) |
98% min |
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Storage |
≤4°C |
Transport Information of Ethylboronic acid丨CAS 4433-63-0
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Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2931900090999 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place. 2~8 deg.C |
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Condition to Avoid |
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Package |
Applications of Ethylboronic acid丨CAS 4433-63-0
1. Organic Synthesis
Widely used as a building block in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds.
Enables the formation of aryl-alkyl or alkyl-alkyl bonds by coupling ethylboronic acid with aryl or vinyl halides.
Provides an efficient route to synthesize pharmaceuticals, agrochemicals, and functional organic molecules.
2. Material Science
Used to functionalize surfaces and prepare boron-containing polymers.
Can act as a precursor to synthesize boronate esters, useful for reversible covalent chemistry in sensing and self-healing materials.
3. Chemical Biology
Boronic acids, including ethylboronic acid, serve as enzyme inhibitors (e.g., protease inhibitors) or molecular recognition elements due to their ability to bind sugars and diols.
Benefits
Versatile coupling partner: Ethylboronic acid's stability and reactivity make it highly valuable in complex molecule synthesis.
Mild reaction conditions: Facilitates coupling under relatively mild and tolerant conditions, preserving sensitive functional groups.
Reversible covalent interactions: Useful in designing responsive and adaptive materials.
Low toxicity: Compared to other organoboron compounds, generally regarded as safe in handling with standard precautions.
Summary
Ethylboronic acid丨CAS 4433-63-0 is a key organoboron reagent widely used in modern organic synthesis, especially for carbon-carbon bond formation via Suzuki coupling. Its boronic acid functionality also enables unique applications in materials science and chemical biology due to its reversible bonding and mild reactivity.
