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Specifications of Disodium hydrogenphosphate dihydrate丨CAS 10028-24-7
|
Grade |
EP11 |
|
Description |
Appearance: White or almost white powder or colourless crystals. |
|
Solubility |
Soluble in water, practically insoluble in ethanol (96 per cent). |
|
Assay |
98.0%~101.0%, calculated on the dried basis. |
|
Identification |
A: Solution S is slightly alkaline. |
|
Tests |
Appearance of solution: Solution S is clear and colorless. |
|
Microbial limit |
Total aerobic bacteria count: 1000 cfu/g max |
Chemical Overview
Disodium hydrogenphosphate dihydrate丨CAS 10028-24-7 is a water-soluble, alkaline salt commonly used in buffering systems, nutritional formulations, chemical manufacturing, and laboratory reagents.
Applications
1. Buffering Agent
Maintains stable pH in a wide range of industrial and biological systems.
Widely used in:
Pharmaceutical formulations
Biotechnology processes
Laboratory-grade buffers (e.g., PBS – phosphate-buffered saline)
Ensures enzyme activity and protein stability during biochemical assays.
2. Food Industry
Used as a food additive (E339(ii)) for:
Emulsifying processed cheeses
Controlling acidity in powdered drink mixes, dairy products, and baked goods
Stabilizing whipped or aerated foods
Functions as a preservative and texturizer in various food applications.
3. Water Treatment
Acts as a phosphate source to prevent corrosion and scale formation in municipal and industrial water systems.
Helps stabilize pH in boiler feedwater and cooling towers.
4. Pharmaceutical and Medical Uses
Used in oral rehydration solutions, antacids, and laxatives.
Supports electrolyte balance and osmotic regulation.
Incorporated in eye drops, dialysis fluids, and nutritional supplements.
5. Cleaning Agents and Detergents
Included in detergents as a water softener and alkaline buffer.
Enhances the cleaning efficiency of industrial and household cleaning products.
6. Fertilizers
Sometimes used in fertilizer blends as a phosphorus source, supporting plant root development and energy transfer (ATP production).
Benefits
1. Excellent Buffering Capacity
Maintains pH stability across a wide range of conditions (especially in the slightly alkaline range).
Ideal for biological systems, preventing pH fluctuations that could damage sensitive proteins or enzymes.
2. High Water Solubility
Dissolves quickly and easily, allowing fast dispersion in aqueous systems.
Suitable for liquid formulations, injection-grade solutions, and high-volume processing.
3. Biocompatible and Safe
Recognized as Generally Recognized As Safe (GRAS) in food and pharmaceutical uses.
Low toxicity and well-tolerated in clinical and nutritional applications.
4. Multi-Functional Utility
Functions as a stabilizer, emulsifier, acidity regulator, nutrient source, and chelating agent across industries.
Reduces the need for multiple additive ingredients, simplifying formulations.
5. Cost-Effective and Readily Available
Produced at scale and widely available, making it an economical choice for large-scale industrial applications.
Conclusion
Disodium hydrogenphosphate dihydrate丨CAS 10028-24-7 is a highly versatile inorganic salt widely used in food, pharmaceutical, water treatment, laboratory, and industrial applications. Its combination of pH buffering, solubility, safety, and cost-efficiency makes it a foundational ingredient in both everyday consumer products and specialized scientific uses. Whether stabilizing food textures, maintaining enzyme function, or balancing electrolytes, it plays a crucial role in formulation science and process control.
