4-Bromo-1-indanone丨CAS 15115-60-3

4-Bromo-1-indanone, with the Chemical Abstracts Service (CAS) number 15115-60-3, is an organic compound. It is a brominated derivative of 1-indanone, featuring a bromine atom at the 4-position of the indanone ring. This compound is widely used in organic synthesis and pharmaceutical research due to its reactivity and versatility as a building block for more complex molecules.

1. Organic Synthesis:

- Building Block: 4-Bromo-1-indanone is a valuable intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and fine chemicals. Its bromine atom makes it highly reactive in substitution and coupling reactions.

- Palladium-Catalyzed Reactions: It is used in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to form carbon-carbon bonds and create complex aromatic structures.

2. Pharmaceutical Research:

- Drug Development: 4-Bromo-1-indanone丨15115-60-3 serves as a precursor in the synthesis of biologically active molecules, including potential drugs for neurological disorders, cancer, and inflammation.

- Structure-Activity Relationship (SAR) Studies: It is used to study the relationship between chemical structure and biological activity, aiding in the design of new therapeutic agents.

3. Material Science:

- Organic Electronics: 4-Bromo-1-indanone is used in the synthesis of organic semiconductors and conductive polymers, which are essential components in organic light-emitting diodes (OLEDs) and solar cells.

- Ligand Synthesis: It is used to prepare ligands for metal complexes, which have applications in catalysis and materials science.

4. Research and Development:

- Chemical Probes: 4-Bromo-1-indanone is used as a chemical probe to study reaction mechanisms and explore new synthetic pathways.

- Fluorescent Dyes: It is a precursor in the synthesis of fluorescent dyes and markers for biological imaging and diagnostics.

1. Reactivity:

- The presence of a bromine atom at the 4-position makes 4-Bromo-1-indanone丨15115-60-3 highly reactive, enabling its use in a wide range of chemical transformations.

2. Versatility:

- Its applications span organic synthesis, pharmaceutical research, and material science, highlighting its versatility as a chemical building block.

3. Drug Discovery:

- Its role as a precursor in the synthesis of biologically active molecules makes it valuable in drug discovery and development.

4. Material Properties:

- Its use in the synthesis of organic semiconductors and conductive polymers contributes to advancements in organic electronics and renewable energy technologies.

5. Research Utility:

- 4-Bromo-1-indanone is a valuable tool in chemical research, enabling the exploration of new reactions and the development of novel compounds.

1. Chemical Safety:

- 4-Bromo-1-indanone丨15115-60-3 should be handled with care, as it may cause irritation to the skin, eyes, and respiratory system. Proper personal protective equipment (PPE), such as gloves, goggles, and lab coats, should be worn when handling this compound.

2. Storage:

- It should be stored in a cool, dry place, away from incompatible materials such as strong oxidizing agents. Proper labeling and storage conditions are essential to ensure safety.

3. Environmental Impact:

- Brominated compounds can be harmful to the environment, so proper disposal methods should be followed to minimize environmental impact. Waste should be disposed of in accordance with local regulations.

4-Bromo-1-indanone丨15115-60-3 is a versatile and reactive compound with applications in organic synthesis, pharmaceutical research, and material science. Its role as a building block for complex molecules and its contributions to drug discovery and organic electronics make it an indispensable tool in chemical research and industrial applications. While it offers numerous benefits, proper handling and disposal practices are essential to ensure its safe and effective use. As research and technology continue to advance, 4-Bromo-1-indanone will remain a key component in the development of new materials, drugs, and chemical processes.